دورية أكاديمية

Targeting Risk Factors for the Control of Central Line-Associated Bloodstream Infection in the Neonatal Intensive Care Unit: A Single Tertiary Center Experience

التفاصيل البيبلوغرافية
العنوان: Targeting Risk Factors for the Control of Central Line-Associated Bloodstream Infection in the Neonatal Intensive Care Unit: A Single Tertiary Center Experience
المؤلفون: Jiyoon Jeong, Yoojin Kwun, Min-ju Kim, Sang-Ho Choi, Euiseok Jung, Byong Sop Lee, Ki-Soo Kim, Ellen Ai-Rhan Kim
المصدر: Neonatal Medicine, Vol 28, Iss 3, Pp 116-123 (2021)
بيانات النشر: Korean Society of Neonatology, 2021.
سنة النشر: 2021
المجموعة: LCC:Pediatrics
مصطلحات موضوعية: central venous catheter, sepsis, neonatal, risk factors, neonatal intensive care unit, quality improvement, Pediatrics, RJ1-570
الوصف: Purpose The aim of this study was to estimate the effect of targeting risk factors for the control of central line-associated bloodstream infection (CLABSI) among high-risk infants in a tertiary neonatal intensive care unit (NICU). Methods Infants admitted to the NICU and diagnosed with CLABSI from January to December 2013 were eligible for inclusion to the study. The CLABSI group (n=47) was matched in a 1:2 ratio to the control group (n=94) based on gestational age, birth weight, and Score for Neonatal Acute Physiology-II. Risk factors for CLABSI were identified using the Cox proportional hazard model, and analysis of the effect of these risk factors targeting infection control was performed. Results The risk factors associated with CLABSI were prolonged central line dwell days (adjusted hazard ratio [HR], 1.028; 95% confidence interval [CI], 1.011 to 1.045; P=0.001), use of a silicone catheter (adjusted HR, 5.895; 95% CI, 1.893 to 18.355; P=0.002), surgical treatment (adjusted HR, 3.793; 95% CI, 1.467 to 9.805; P=0.006), and less probiotic supplementation (adjusted HR, 0.254; 95% CI, 0.068 to 0.949; P=0.042). By targeting these risk factors with a quality improvement initiative, the mean CLABSI incidence rate per 1,000 catheter-days decreased from 6.6 to 3.1 (P=0.004). Conclusion Targeting risk factors for infection control significantly reduced the rate of CLABSI among high-risk infants in the NICU.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Korean
تدمد: 2287-9412
2287-9803
Relation: http://www.neo-med.org/upload/pdf/nm-2021-28-3-116.pdf; https://doaj.org/toc/2287-9412; https://doaj.org/toc/2287-9803
DOI: 10.5385/nm.2021.28.3.116
URL الوصول: https://doaj.org/article/2e1016a4c08e4887a5ac05bbce73044e
رقم الأكسشن: edsdoj.2e1016a4c08e4887a5ac05bbce73044e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22879412
22879803
DOI:10.5385/nm.2021.28.3.116