دورية أكاديمية
أعرض في EDS

Levosimendan in outpatients with advanced heart failure: Single-center experience of 200 intermittent perfusions

التفاصيل البيبلوغرافية
العنوان: Levosimendan in outpatients with advanced heart failure: Single-center experience of 200 intermittent perfusions
المؤلفون: João Ferreira Reis, António Valentim Gonçalves, Rita Ilhão Moreira, Tiago Pereira da Silva, Ana Teresa Timóteo, Delmira Pombo, Tiago Carvalho, Catarina Correia, Claúdia Santos, Rui Cruz Ferreira
المصدر: Revista Portuguesa de Cardiologia, Vol 42, Iss 4, Pp 335-343 (2023)
بيانات النشر: Elsevier, 2023.
سنة النشر: 2023
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: Insuficiência cardíaca avançada, Levosimendan, Hospital de dia, Transplante cardíaco, Qualidade de vida, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Introduction: Patients with advanced heart failure (HF) have high morbidity and mortality, with only a small proportion being eligible for advanced therapies. Intermittent outpatient levosimendan infusion has been shown to provide symptomatic relief and reduce the rate of HF events. Our aim was to assess the safety and efficacy of outpatient levosimendan administration in an advanced HF population. Methods: This is a report of a single-center experience of consecutive advanced HF patients referred for intermittent intravenous outpatient administration of levosimendan, between January 2018 and March 2021. Baseline and follow-up evaluation included clinical assessment, laboratory tests, transthoracic echocardiography and cardiopulmonary exercise testing. Baseline and clinical follow-up data were compared using the Wilcoxon signed-rank test. Results: A total of 24 patients (60.8 years, 83% male, mean left ventricular ejection fraction [LVEF] 24%), with a median of 1.5 HF hospitalizations in the previous six months, were referred for outpatient levosimendan pulses, the majority as a bridge to transplantation or due to clinical deterioration. At six-month follow-up there was a significant reduction in HF hospitalizations to 0.4±0.7 (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Portuguese
تدمد: 0870-2551
Relation: http://www.sciencedirect.com/science/article/pii/S0870255123000483; https://doaj.org/toc/0870-2551
DOI: 10.1016/j.repc.2022.03.006
URL الوصول: https://doaj.org/article/2e5eafd4d7f345409df2e52f3433b9e3
رقم الأكسشن: edsdoj.2e5eafd4d7f345409df2e52f3433b9e3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:08702551
DOI:10.1016/j.repc.2022.03.006