دورية أكاديمية

Global burden of liver cirrhosis and other chronic liver diseases caused by specific etiologies from 1990 to 2019

التفاصيل البيبلوغرافية
العنوان: Global burden of liver cirrhosis and other chronic liver diseases caused by specific etiologies from 1990 to 2019
المؤلفون: Xiao-Ning Wu, Feng Xue, Nan Zhang, Wei Zhang, Jing-Jing Hou, Yi Lv, Jun-Xi Xiang, Xu-Feng Zhang
المصدر: BMC Public Health, Vol 24, Iss 1, Pp 1-15 (2024)
بيانات النشر: BMC, 2024.
سنة النشر: 2024
المجموعة: LCC:Public aspects of medicine
مصطلحات موضوعية: Liver cirrhosis, Chronic liver disease, Global burden of disease 2019, Mortality, Incidence, Public aspects of medicine, RA1-1270
الوصف: Abstract Background This study aimed to assess the global, regional, and national burden of liver cirrhosis and other chronic liver diseases between 1990 and 2019, considering five etiologies (hepatitis B, hepatitis C, alcohol use, NAFLD and other causes), age, gender, and sociodemographic index (SDI). Methods Data on liver cirrhosis and other chronic liver diseases mortality, incidence, and disability-adjusted life years (DALYs) were collected from the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2019. Results In 2019, liver cirrhosis and other chronic liver diseases accounted for 1,472,011 (95% UI 1,374,608-1,578,731) deaths worldwide, compared to 1,012,975 (948,941-1,073,877) deaths in 1990. Despite an increase in absolute deaths, the age-standardized death rate declined from 24.43 (22.93–25.73) per 100,000 population in 1990 to 18.00 (19.31–16.80) per 100,000 population in 2019. Eastern sub-Saharan Africa exhibited the highest age-standardized death rate (44.15 [38.47–51.91] per 100,000 population), while Australasia had the lowest rate (5.48 [5.05–5.93] deaths per 100,000 population in 2019). The age-standardized incidence rate of liver cirrhosis and other chronic liver diseases attributed to hepatitis B virus has declined since 1990, but incidence rates for other etiologies have increased. Age-standardized death and DALYs rates progressively decreased with higher SDI across different GBD regions and countries. Mortality due to liver cirrhosis and other chronic liver diseases increased with age in 2019, and the death rate among males was estimated 1.51 times higher than that among females globally. Conclusion Liver cirrhosis and other chronic liver diseases continues to pose a significant global public health challenge. Effective disease control, prevention, and treatment strategies should account for variations in risk factors, age, gender, and regional disparities.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2458
Relation: https://doaj.org/toc/1471-2458
DOI: 10.1186/s12889-024-17948-6
URL الوصول: https://doaj.org/article/ce2eae90a2464f88b9d4b575d0648bc1
رقم الأكسشن: edsdoj.2eae90a2464f88b9d4b575d0648bc1
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712458
DOI:10.1186/s12889-024-17948-6