دورية أكاديمية
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials
| العنوان: | The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
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| المؤلفون: | Mariana Leonel Martins, Karla Lorene de França Leite, Marcela Baraúna Magno, Daniele Masterson, José Miguel Vicente-Gomila, Yuri Wanderley Cavalcanti, Lucianne Cople Maia, Andréa Fonseca-Gonçalves |
| المصدر: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada, Vol 22 (2022) |
| بيانات النشر: | Association of Support to Oral Health Research (APESB), 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Dentistry |
| مصطلحات موضوعية: | Xylitol, Therapeutics, Randomized Controlled Trials as Topic, Bibliometrics, Dentistry, RK1-715 |
| الوصف: | Objective: To describe and evaluate the xylitol products’ applicability and its effects in the health area worldwide utilizing a bibliometric analysis from randomized controlled trials (RCT) with humans. Material and Methods: Electronic searches were carried out in Medline/PubMed, Scopus, Cochrane Library, Web of Science, and VHL databases. The main data extracted were: year, area of applicability, type of treatment, country, journal, xylitol posology and concentration, presentation form, outcomes, and effects. Results: From 1476 studies, 257 were included. These studies were published between 1973-2021. The majority was carried out in dentistry (73.9%) and under preventive treatment (67.4%). These studies were developed in the USA (15.4%) and published in Caries Research (6.6%). The posology and concentration ranged between 0.004-67 g/day and 0.002-100%, respectively. The xylitol is usually used in the chewing gum form (44.0%), and for antimicrobial activity evaluation (38.5%). A positive effect was observed in 204 studies (79.3%) and was associated with xylitol concentration ≥ 15% (p=0.007). Side effects were reported in 8.2% and were associated with posology ≥ 5 g/day (p=0.03). Conclusion: Most studies with xylitol were conducted to prevent diseases in the dentistry field. The chewing gum form and antimicrobial activity evaluation were more frequent. Most xylitol products have a positive effect, and few studies report side effects. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 1519-0501 1983-4632 |
| Relation: | https://revista.uepb.edu.br/PBOCI/article/view/972; https://doaj.org/toc/1519-0501; https://doaj.org/toc/1983-4632 |
| URL الوصول: | https://doaj.org/article/e2eb051666e34afa91d44563ad201269 |
| رقم الأكسشن: | edsdoj.2eb051666e34afa91d44563ad201269 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15190501 19834632 |
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