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The association between intrauterine inflammation and spontaneous vaginal delivery at term: a cross-sectional study.

التفاصيل البيبلوغرافية
العنوان: The association between intrauterine inflammation and spontaneous vaginal delivery at term: a cross-sectional study.
المؤلفون: Michiel L Houben, Peter G J Nikkels, Grada M van Bleek, Gerard H A Visser, Maroeska M Rovers, Hilda Kessel, Wouter J de Waal, Leontine Schuijff, Annemiek Evers, Jan L L Kimpen, Louis Bont
المصدر: PLoS ONE, Vol 4, Iss 8, p e6572 (2009)
بيانات النشر: Public Library of Science (PLoS), 2009.
سنة النشر: 2009
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: BACKGROUND:Different factors contribute to the onset of labor at term. In animal models onset of labor is characterized by an inflammatory response. The role of intrauterine inflammation, although implicated in preterm birth, is not yet established in human term labor. We hypothesized that intrauterine inflammation at term is associated with spontaneous onset of labor. METHODS/RESULTS:In two large urban hospitals in the Netherlands, a cross-sectional study of spontaneous onset term vaginal deliveries and elective caesarean sections (CS), without signs of labor, was carried out. Placentas and amniotic fluid samples were collected during labor and/or at delivery. Histological signs of placenta inflammation were determined. Amniotic fluid proinflammatory cytokine concentrations were measured using ELISA. A total of 375 women were included. In term vaginal deliveries, more signs of intrauterine inflammation were found than in elective CS: the prevalence of chorioamnionitis was higher (18 vs 4%, p = 0.02) and amniotic fluid concentration of IL-6 was higher (3.1 vs 0.37 ng/mL, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC2718580?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0006572
URL الوصول: https://doaj.org/article/2f27d7d28ddc4d01895ca01b35f43a0d
رقم الأكسشن: edsdoj.2f27d7d28ddc4d01895ca01b35f43a0d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0006572