دورية أكاديمية
Association Between Myopia and Pupil Diameter in Preschoolers: Evidence from a Machine Learning Approach Based on a Real-World Large-Scale Dataset
| العنوان: | Association Between Myopia and Pupil Diameter in Preschoolers: Evidence from a Machine Learning Approach Based on a Real-World Large-Scale Dataset |
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| المؤلفون: | Shengsong Xu, Linling Li, Wenjing Han, Yingting Zhu, Yin Hu, Zhidong Li, Zhenbang Ruan, Zhuandi Zhou, Yehong Zhuo, Min Fu, Xiao Yang |
| المصدر: | Ophthalmology and Therapy, Vol 13, Iss 7, Pp 2009-2022 (2024) |
| بيانات النشر: | Adis, Springer Healthcare, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Ophthalmology |
| مصطلحات موضوعية: | Child health, Optics and refraction, Pediatrics, Pupil, Public health, Ophthalmology, RE1-994 |
| الوصف: | Abstract Introduction Previous studies have explored the connections between various ocular biological parameters with myopia. Our previous study also found that pupil data can predict the myopic progression during the interventions for myopia. However, studies exploring the association between pupil diameter and myopia in preschoolers with myopia were lacking. Hence this study was aimed to investigate the association between pupil diameter and myopia in preschoolers with myopia based on a real-world, large-scale dataset. Methods Data containing 650,671 preschoolers were collected from a total of 1943 kindergartens in Shenzhen, China. Refraction and pupil parameters were collected. After data filtering, the occurrence of myopia and its association with age, gender, pupil diameter, and other variables, were analyzed. Random forest (RF) and eXtreme gradient boosting (XGBoost) were selected from seven machine learning algorithms to build the model. The mean decrease accuracy (MDA), mean decrease Gini (MDG), and gain feature importance (GFI) techniques were employed to quantify the importance of pupil diameter and other features. Results After the assessments, 51,325 valid records with complete pupil data were included, and 3468 (6.76%) were identified as myopia based on the calculated cycloplegic refraction. Preschoolers with myopia presented reduced pupil diameter and greater variation (5.00 ± 0.99 mm) compared to non-myopic preschoolers (6.22 ± 0.67 mm). A nonlinear relationship was found according to the scatterplots between pupil diameter and refraction (R 2 = 0.14). Especially preschoolers with myopia had reduced pupil diameter compared to emmetropic preschoolers, but hyperope did not experience additional pupil enlargement. After adjusting for other covariates, this relationship is still consistent (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2193-8245 2193-6528 |
| Relation: | https://doaj.org/toc/2193-8245; https://doaj.org/toc/2193-6528 |
| DOI: | 10.1007/s40123-024-00972-5 |
| URL الوصول: | https://doaj.org/article/3048728670da4da18566ecb435d08fce |
| رقم الأكسشن: | edsdoj.3048728670da4da18566ecb435d08fce |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 21938245 21936528 |
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| DOI: | 10.1007/s40123-024-00972-5 |