دورية أكاديمية
ANTIOXIDANT ACTIVITY AND INHIBITORY EFFECT OF 2,4,4'-TRIHYDROXYCHALCONE ON DIGESTIVE ENZYMES RELATED TO OBESITY
| العنوان: | ANTIOXIDANT ACTIVITY AND INHIBITORY EFFECT OF 2,4,4'-TRIHYDROXYCHALCONE ON DIGESTIVE ENZYMES RELATED TO OBESITY |
|---|---|
| المؤلفون: | Hadeil Alsufiani, Ghaynat A. Aldhaheri, Ulfat M. Omar, Taraji M. Bahdilah, Rasha A. Mansouri |
| المصدر: | Slovenian Veterinary Research, Vol 60, Iss 25-Suppl (2023) |
| بيانات النشر: | University of Ljubljana Press (Založba Univerze v Ljubljani), 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Veterinary medicine |
| مصطلحات موضوعية: | 2,4,4'-trihydroxychalcone, DPPH radical scavenging activity, reducing power, ferrous ion chelating activity, sucrase, α-amylase, Veterinary medicine, SF600-1100 |
| الوصف: | The aim of this study was to investigate the antioxidant activity and inhibitory effect of 2,4,4'-trihydroxychalcone on digestive enzymes related to obesity, including sucrase, α-amylase, and lipase. The in vitro antioxidant activities of three concentrations of 2,4,4'-trihydroxychalcone (100, 300, and 500 µg/ml) were determined using 2,2-diphenyl-1-picrylhydrazyl radical scavenging, reducing power, and ferrous ion chelating assays. Moreover, in vitro inhibition of lipase, α-amylase, and sucrase enzyme activities by 2,4,4'-trihydroxychalcone was determined using a specific assay for each enzyme. 2,4,4'-Trihydroxychalcone has been shown to have antioxidant properties and inhibits sucrase, α-amylase and lipase activities. These findings suggest that 2,4,4′-trihydroxychalcone demonstrated an antioxidant activity and can effectively inhibit the key enzymes related to obesity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Slovenian |
| تدمد: | 1580-4003 2385-8761 30739179 |
| Relation: | https://www.slovetres.si/index.php/SVR/article/view/1625; https://doaj.org/toc/1580-4003; https://doaj.org/toc/2385-8761 |
| DOI: | 10.26873/SVR-1625-2022 |
| URL الوصول: | https://doaj.org/article/30739179ab7f4e71833dff04a42d19ca |
| رقم الأكسشن: | edsdoj.30739179ab7f4e71833dff04a42d19ca |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15804003 23858761 30739179 |
|---|---|
| DOI: | 10.26873/SVR-1625-2022 |