دورية أكاديمية
Prospective role of lusianthridin in attenuating cadmium-induced functional and cellular damage in rat thyroid
| العنوان: | Prospective role of lusianthridin in attenuating cadmium-induced functional and cellular damage in rat thyroid |
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| المؤلفون: | Teng Gao, Sijia Luo, Hongguang Li, Zijie Su, Qinghui Wen |
| المصدر: | Heliyon, Vol 10, Iss 5, Pp e27080- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Science (General) LCC:Social sciences (General) |
| مصطلحات موضوعية: | Lusianthridin, Deiodinase, Lipid, Antioxidant, mRNA, Science (General), Q1-390, Social sciences (General), H1-99 |
| الوصف: | The thyroid represents the most prevalent form of head and neck and endocrine cancer. The present investigation demonstrates the anticancer effects of Lusianthridin against cadmium (Cd)-induced thyroid cancer in rats. Swiss Wistar rats were utilized in this experimental study. Cd was employed to induce thyroid cancer, and the rats were divided into different groups, receiving oral administration of Lusianthridin (20 mg/kg) for 14 days. Thyroid parameters, deiodinase levels, hepatic parameters, lipid parameters, and antioxidant parameters were respectively estimated. The mRNA expression was assessed using real-time reverse transcriptase polymerase chain reaction (RT-PCR). Lusianthridin significantly (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2405-8440 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2405844024031116; https://doaj.org/toc/2405-8440 |
| DOI: | 10.1016/j.heliyon.2024.e27080 |
| URL الوصول: | https://doaj.org/article/313e6efaf9284ae983fc86a33518b415 |
| رقم الأكسشن: | edsdoj.313e6efaf9284ae983fc86a33518b415 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24058440 |
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| DOI: | 10.1016/j.heliyon.2024.e27080 |