دورية أكاديمية
The impact of Apis dorsata forest honey administration on follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels in rats (Rattus norvegicus) forced swim test as a chronic physical animal model
العنوان: | The impact of Apis dorsata forest honey administration on follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels in rats (Rattus norvegicus) forced swim test as a chronic physical animal model |
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المؤلفون: | Widjiati Widjiati, Epy Muhammad Luqman, Suryo Kuntjorodjakti, Aulanni'am Aulanni'am, Zahra Shabira, Sultan Fadhilla Taqwa, Riski Lesta Mega, Dean Chou, Ahmad Shofy Mubarak, Viski Fitri Hendrawan |
المصدر: | Open Veterinary Journal, Vol 14, Iss 2, Pp 738-742 (2024) |
بيانات النشر: | Tripoli University, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Zoology |
مصطلحات موضوعية: | rattus norvegicus, forced swim test, apis dorsata forest honey, fsh, lh, Zoology, QL1-991 |
الوصف: | Background: Chronic physical stress has many effects on the nervous system and can cause structural changes in different parts of the brain and hemomodulatory, including hormonal. Current pharmacotherapeutic treatments have limited efficacy and are associated with many deleterious side effects Aim: The aim of this research is to determine how apis dorsata forest honey administration affects FSH and LH levels in rats who are subjected to forced swim tests as a model of chronic physical stress placed in a container filled with water from which it cannot escape. Methods: This was an experimental laboratory study with 32 rats divided into four treatment groups: control (C), Treatment 1 (T1) with a forced swim test + honey (2 g/rat/day), Treatment 2 (T2) with a forced swim test + honey (4 g/rat/day), and Treatment 3 (T3) with a forced swim test + honey (6 g/rat/day). All treatments were administered for 14 days. Then blood was taken for FSH and LH serum tests, and a one-way ANOVA and Duncan test were used to statistically test the data analysis. Results: The results of this study indicate that the administration of forest honey had no significant effect (p > 0.05) on the FSH parameter, but there was a significant decrease in LH levels in the T2 and T3 groups (p [Open Vet J 2024; 14(2.000): 738-742] |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2226-4485 2218-6050 |
Relation: | https://www.openveterinaryjournal.com/?mno=174251; https://doaj.org/toc/2226-4485; https://doaj.org/toc/2218-6050 |
DOI: | 10.5455/OVJ.2024.v14.i2.14 |
URL الوصول: | https://doaj.org/article/31a9dd41f2ab4660b6720c2e7d293416 |
رقم الأكسشن: | edsdoj.31a9dd41f2ab4660b6720c2e7d293416 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22264485 22186050 |
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DOI: | 10.5455/OVJ.2024.v14.i2.14 |