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Modulation of Free Amino Acid Profile in Healthy Humans Administered with Mastiha Terpenes. An Open-Label Trial

التفاصيل البيبلوغرافية
العنوان: Modulation of Free Amino Acid Profile in Healthy Humans Administered with Mastiha Terpenes. An Open-Label Trial
المؤلفون: Efstathia Papada, Ljilja Torović, Charalampia Amerikanou, Nikolaos Kalogeropoulos, Ilias Smyrnioudis, Andriana C. Kaliora
المصدر: Nutrients, Vol 10, Iss 6, p 715 (2018)
بيانات النشر: MDPI AG, 2018.
سنة النشر: 2018
المجموعة: LCC:Nutrition. Foods and food supply
مصطلحات موضوعية: plasma-free amino acids, terpenes, GC-MS metabolic analysis, uric acid, Nutrition. Foods and food supply, TX341-641
الوصف: We aimed to explore whether plasma-free amino acids are modified in response to terpenes administration in healthy humans. In this open-label, single-arm acute trial, seventeen healthy male volunteers were administered with a naturally occurring product of known terpenes—namely mastiha—after overnight fasting. Blood samples were collected at different time points before and after ingestion. We aimed at identifying and quantifying 60 free amino acids in plasma applying Gas Chromatography-Mass Spectrometry. A total of 24 free amino acids were quantified. Branched-chain valine significantly decreased 4 h post-ingestion, whereas proline decreased at 6 h and ornithine at 2 h, compared to 0 h. These novel findings demonstrate that free amino acids levels are modulated in response to terpenes intake in healthy subjects.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2072-6643
10060715
Relation: http://www.mdpi.com/2072-6643/10/6/715; https://doaj.org/toc/2072-6643
DOI: 10.3390/nu10060715
URL الوصول: https://doaj.org/article/d32d570bc84642ff90fd6ee060d95344
رقم الأكسشن: edsdoj.32d570bc84642ff90fd6ee060d95344
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20726643
10060715
DOI:10.3390/nu10060715