دورية أكاديمية
Modulation of Free Amino Acid Profile in Healthy Humans Administered with Mastiha Terpenes. An Open-Label Trial
العنوان: | Modulation of Free Amino Acid Profile in Healthy Humans Administered with Mastiha Terpenes. An Open-Label Trial |
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المؤلفون: | Efstathia Papada, Ljilja Torović, Charalampia Amerikanou, Nikolaos Kalogeropoulos, Ilias Smyrnioudis, Andriana C. Kaliora |
المصدر: | Nutrients, Vol 10, Iss 6, p 715 (2018) |
بيانات النشر: | MDPI AG, 2018. |
سنة النشر: | 2018 |
المجموعة: | LCC:Nutrition. Foods and food supply |
مصطلحات موضوعية: | plasma-free amino acids, terpenes, GC-MS metabolic analysis, uric acid, Nutrition. Foods and food supply, TX341-641 |
الوصف: | We aimed to explore whether plasma-free amino acids are modified in response to terpenes administration in healthy humans. In this open-label, single-arm acute trial, seventeen healthy male volunteers were administered with a naturally occurring product of known terpenes—namely mastiha—after overnight fasting. Blood samples were collected at different time points before and after ingestion. We aimed at identifying and quantifying 60 free amino acids in plasma applying Gas Chromatography-Mass Spectrometry. A total of 24 free amino acids were quantified. Branched-chain valine significantly decreased 4 h post-ingestion, whereas proline decreased at 6 h and ornithine at 2 h, compared to 0 h. These novel findings demonstrate that free amino acids levels are modulated in response to terpenes intake in healthy subjects. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2072-6643 10060715 |
Relation: | http://www.mdpi.com/2072-6643/10/6/715; https://doaj.org/toc/2072-6643 |
DOI: | 10.3390/nu10060715 |
URL الوصول: | https://doaj.org/article/d32d570bc84642ff90fd6ee060d95344 |
رقم الأكسشن: | edsdoj.32d570bc84642ff90fd6ee060d95344 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20726643 10060715 |
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DOI: | 10.3390/nu10060715 |