دورية أكاديمية
cis–trans Isomerization of silybins A and B
| العنوان: | cis–trans Isomerization of silybins A and B |
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| المؤلفون: | Michaela Novotná, Radek Gažák, David Biedermann, Florent Di Meo, Petr Marhol, Marek Kuzma, Lucie Bednárová, Kateřina Fuksová, Patrick Trouillas, Vladimír Křen |
| المصدر: | Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 1047-1063 (2014) |
| بيانات النشر: | Beilstein-Institut, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Science LCC:Organic chemistry |
| مصطلحات موضوعية: | 2,3-cis-silybin, 10,11-cis-silybin, isomerization, silibinin, silybin, silymarin, Science, Organic chemistry, QD241-441 |
| الوصف: | Methods were developed and optimized for the preparation of the 2,3-cis- and the 10,11-cis-isomers of silybin by the Lewis acid catalyzed (BF3∙OEt2) isomerization of silybins A (1a) and B (1b) (trans-isomers). The absolute configuration of all optically pure compounds was determined by using NMR and comparing their electronic circular dichroism data with model compounds of known absolute configurations. Mechanisms for cis–trans-isomerization of silybin are proposed and supported by quantum mechanical calculations. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1860-5397 |
| Relation: | https://doaj.org/toc/1860-5397 |
| DOI: | 10.3762/bjoc.10.105 |
| URL الوصول: | https://doaj.org/article/32eceaea79cc4b569924581b8eaffe3e |
| رقم الأكسشن: | edsdoj.32eceaea79cc4b569924581b8eaffe3e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18605397 |
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| DOI: | 10.3762/bjoc.10.105 |