دورية أكاديمية
Antioxidant and antiproliferative activities of proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves
| العنوان: | Antioxidant and antiproliferative activities of proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves |
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| المؤلفون: | Yu Zhang, Xiaozhou Zhou, Wenyang Tao, Lanqi Li, Chaoyang Wei, Jie Duan, Shiguo Chen, Xingqian Ye |
| المصدر: | Journal of Functional Foods, Vol 27, Iss , Pp 645-654 (2016) |
| بيانات النشر: | Elsevier, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Nutrition. Foods and food supply |
| مصطلحات موضوعية: | Proanthocyanidins, Chinese bayberry leaves, Ultrasonic degradation, Cellular antioxidant activity (CAA), Antiproliferation, Nutrition. Foods and food supply, TX341-641 |
| الوصف: | Chinese bayberry leaves proanthocyanidin (BLPs) contain epigallocatechin-3-O- gallate (EGCG) as its terminal unit and most of its extension units, which is unusual in the plant kingdom. The present study compared the antioxidant and anti-proliferative activities of BLPs prepared from different purification stages. Low-molecular-weight BLPs were prepared by ultrasonic treatment. Results revealed that the antioxidant activities of BLPs were strongly related to the content of total phenolics and proanthocyanidins; however, the cellular assay indicated that the mean degree of polymerization (mDP) played a vital role in the cellular antioxidant activity (CAA) of BLPs. The ultrasonic depolymerized BLPs with lower mDP (3.6 ± 0.3) exhibited a much higher CAA (EC50 = 0.042 ± 0.005 mg/mL) than other groups, which suggests that bioavailability is crucial to the cellular antioxidant potential of BLPs. Additionally, BLPs strongly inhibited HepG2 proliferation in a dose-dependent manner. Our results indicated that BLPs could be a valuable resource of bioactive compounds to promote consumer health. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1756-4646 33658609 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1756464616303176; https://doaj.org/toc/1756-4646 |
| DOI: | 10.1016/j.jff.2016.10.004 |
| URL الوصول: | https://doaj.org/article/3365860929d349b787488cfa08196c9a |
| رقم الأكسشن: | edsdoj.3365860929d349b787488cfa08196c9a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17564646 33658609 |
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| DOI: | 10.1016/j.jff.2016.10.004 |