دورية أكاديمية
Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q)
العنوان: | Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q) |
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المؤلفون: | Pierre Fenaux, Aristoteles Giagounidis, Dominik Selleslag, Odile Beyne-Rauzy, Moshe Mittelman, Petra Muus, Stephen D. Nimer, Eva Hellström-Lindberg, Bayard L. Powell, Agnes Guerci-Bresler, Mikkael A. Sekeres, H. Joachim Deeg, Consuelo del Cañizo, Peter L. Greenberg, Jamile M. Shammo, Barry Skikne, Xujie Yu, Alan F. List |
المصدر: | Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-8 (2017) |
بيانات النشر: | BMC, 2017. |
سنة النشر: | 2017 |
المجموعة: | LCC:Diseases of the blood and blood-forming organs LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | Acute myeloid leukemia, del(5q), Lenalidomide, Myelodysplastic syndromes, Age, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Abstract Background Particularly since the advent of lenalidomide, lower-risk myelodysplastic syndromes (MDS) patients with del(5q) have been the focus of many studies; however, the impact of age on disease characteristics and response to lenalidomide has not been analyzed. Methods We assessed the effect of age on clinical characteristics and outcomes in 286 lenalidomide-treated MDS patients with del(5q) from two multicenter trials. Results A total of 33.9, 34.3, and 31.8% patients were aged |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1756-8722 |
Relation: | http://link.springer.com/article/10.1186/s13045-017-0491-2; https://doaj.org/toc/1756-8722 |
DOI: | 10.1186/s13045-017-0491-2 |
URL الوصول: | https://doaj.org/article/e33788a17f6a499d88585d724ce72be7 |
رقم الأكسشن: | edsdoj.33788a17f6a499d88585d724ce72be7 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17568722 |
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DOI: | 10.1186/s13045-017-0491-2 |