دورية أكاديمية
Botulinum Neurotoxin Injections in Childhood Opisthotonus
| العنوان: | Botulinum Neurotoxin Injections in Childhood Opisthotonus |
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| المؤلفون: | Mariam Hull, Mered Parnes, Joseph Jankovic |
| المصدر: | Toxins, Vol 13, Iss 2, p 137 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | opisthotonus, opisthotonos, axial dystonia, botulinum toxin, Medicine |
| الوصف: | Opisthotonus refers to abnormal axial extension and arching of the trunk produced by excessive contractions of the paraspinal muscles. In childhood, the abnormal posture is most often related to dystonia in the setting of hypoxic injury or a number of other acquired and genetic etiologies. The condition is often painful, interferes with ambulation and quality of life, and is challenging to treat. Therapeutic options include oral benzodiazepines, oral and intrathecal baclofen, botulinum neurotoxin injections, and deep brain stimulation. Management of opisthotonus within the pediatric population has not been systematically reviewed. Here, we describe a series of seven children who presented to our institution with opisthotonus in whom symptom relief was achieved following administration of botulinum neurotoxin injections. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 13020137 2072-6651 |
| Relation: | https://www.mdpi.com/2072-6651/13/2/137; https://doaj.org/toc/2072-6651 |
| DOI: | 10.3390/toxins13020137 |
| URL الوصول: | https://doaj.org/article/33e78da4bfb74294959619dfcd987ce2 |
| رقم الأكسشن: | edsdoj.33e78da4bfb74294959619dfcd987ce2 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13020137 20726651 |
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| DOI: | 10.3390/toxins13020137 |