دورية أكاديمية
Characterization and antimicrobial, antioxidant, and anti-proliferative activities of green synthesized magnesium oxide nanoparticles with shoot extracts of Plicosepalus curviflorus
| العنوان: | Characterization and antimicrobial, antioxidant, and anti-proliferative activities of green synthesized magnesium oxide nanoparticles with shoot extracts of Plicosepalus curviflorus |
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| المؤلفون: | Reem Hamoud Alrashoudi, Manal Abudawood, Ayesha Mateen, Hajera Tabassum, Noura Ibrahem Alghumlas, Sabiha Fatima, Basmah Almaarik, Farah Maqsood, Nawal M Al Musayeib, Musarat Amina |
| المصدر: | Asian Pacific Journal of Tropical Biomedicine, Vol 13, Iss 7, Pp 315-324 (2023) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Arctic medicine. Tropical medicine LCC:Biology (General) |
| مصطلحات موضوعية: | pc-mgonps, plicosepalus curviflorus, ftir, antimicrobial, cell viability, antioxidant, Arctic medicine. Tropical medicine, RC955-962, Biology (General), QH301-705.5 |
| الوصف: | Objective: To synthesize magnesium oxide nanoparticles using ethanol extract of shoots of Plicosepalus curviflorus (PC-MgONPs) and evaluate the antimicrobial, antioxidant, and anti-proliferative activities of PC-MgONPs. Methods: The green synthesized PC-MgONPs were characterized by ultraviolet-visible (UV), Fourier-transform infrared spectroscopy, zeta potential, energy dispersive X-ray, and scanning electron microscopy. Furthermore, we investigated total antioxidant capacity and antimicrobial and anti-proliferative activities using breast cancer cell lines (MDA-231). Results: The UV spectrum of PC-MgONPs showed a sharp absorption peak at 300 nm. The presence of magnesium, oxygen, and sodium was confirmed by energy dispersive X-ray analysis. Scanning electron microscopy revealed PC-MgONPs as roughly spherical granular structures with sizes ranging from 20.0 to 76.4 nm. PC-MgONPs showed considerable antimicrobial activities against Escherichia coli, Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans with zones of inhibition of 11-17 mm. In addition, total antioxidant capacity and anti-proliferative activity of PC-MgONPs against MDA-231 cells were dose-dependent. Conclusions: The synthesized PC-MgONPs could be a potent antimicrobial, antioxidant and anti-cancer agent, which needs further investigation. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2221-1691 2588-9222 |
| Relation: | http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=7;spage=315;epage=324;aulast=Alrashoudi; https://doaj.org/toc/2221-1691; https://doaj.org/toc/2588-9222 |
| DOI: | 10.4103/2221-1691.380563 |
| URL الوصول: | https://doaj.org/article/d3434b5c92724869a4f6b5fe6a41bcdf |
| رقم الأكسشن: | edsdoj.3434b5c92724869a4f6b5fe6a41bcdf |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22211691 25889222 |
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| DOI: | 10.4103/2221-1691.380563 |