دورية أكاديمية
Lower body mass index is not of more benefit for diabetic complications
| العنوان: | Lower body mass index is not of more benefit for diabetic complications |
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| المؤلفون: | Yongze Zhang, Yangyang Guo, Ximei Shen, Fengying Zhao, Sunjie Yan |
| المصدر: | Journal of Diabetes Investigation, Vol 10, Iss 5, Pp 1307-1317 (2019) |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | Body mass index, Type 2 diabetes mellitus, Vascular complications, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | Abstract Aims/Introduction To investigate the relationship between different body mass index (BMI) levels and vascular complications in type 2 diabetes mellitus patients. Materials and Methods Data were collected from 3,224 individuals with type 2 diabetes mellitus (male/female: 1,635/1,589; age 61.31 ± 11.45 years), using a retrospective case study design. The association of BMI quintiles and diabetes mellitus vascular complications was assessed using multiple logistic regression models adjusting for age, sex, diabetes duration, smoking status, drinking and other confounders, using those with the lowest quintile of BMI as the reference group. Results With increasing BMI, the detection rate of diabetic peripheral neuropathy and peripheral arterial disease initially decreased and then it increased, whereas the detection rate of diabetic kidney disease and carotid atherosclerotic plaques showed an upward trend; however, diabetic retinopathy was irregular. The odds ratios of diabetic peripheral neuropathy decreased as BMI increased from the 21st percentile to the 80th percentile initially, and increased when BMI was in >80th percentile. The same result was shown in peripheral arterial disease. BMI >80th percentile showed a 1.426‐fold risk of diabetic kidney disease and a 1.336 ‐fold risk of carotid atherosclerotic plaque. Conclusions In patients with type 2 diabetes mellitus, the relationship between different BMIs and vascular complications varies. A U‐shaped relationship was observed between BMI and diabetic peripheral neuropathy, as well as BMI and peripheral arterial disease. BMI is positively correlated with diabetic kidney disease and carotid atherosclerotic plaque; however, it is not correlated with diabetic retinopathy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2040-1124 2040-1116 |
| Relation: | https://doaj.org/toc/2040-1116; https://doaj.org/toc/2040-1124 |
| DOI: | 10.1111/jdi.13003 |
| URL الوصول: | https://doaj.org/article/356b9060e15644f592e94ea5cdcb6edf |
| رقم الأكسشن: | edsdoj.356b9060e15644f592e94ea5cdcb6edf |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20401124 20401116 |
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| DOI: | 10.1111/jdi.13003 |