Background: Retinal detachment surgery (RDS) is frequently associated with a high incidence of significant perioperative pain and oculocardiac reflex (OCR) intra-operatively. The peribulbar block has gained wide acceptance in ophthalmic anesthetic practice in the recent times. However, there is little current knowledge regarding its efficacy in RDS. This prospective randomized clinical study evaluated the effect and feasibility of peribulbar block when used in conjunction with general anesthesia on perioperative outcome. Methods: 98 patients, ASA II-III, were randomly allocated to one of two groups to receive either peribulbar block in conjunction with general anesthesia (n = 49) or general anesthesia alone (n = 49). Parameters compared were incidence of OCR, surgical bleeding, duration of surgery, postoperative pain and patient‘s satisfaction. Results and discussion: Patients with PB block had a significantly lower incidence of intraoperative OCR (n = 4 vs. n = 13, p
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