دورية أكاديمية
Monocyte Distribution Width, a Novel Biomarker for Early Sepsis Screening and Comparison with Procalcitonin and C-Reactive Protein
| العنوان: | Monocyte Distribution Width, a Novel Biomarker for Early Sepsis Screening and Comparison with Procalcitonin and C-Reactive Protein |
|---|---|
| المؤلفون: | Fatima Meraj, Sumera Shaikh, Sidra Maqsood, Fatima Kanani, Hamza Khan, Saba Jamal |
| المصدر: | Journal of Laboratory Physicians, Vol 15, Iss 02, Pp 294-299 (2023) |
| بيانات النشر: | Thieme Medical and Scientific Publishers Pvt. Ltd., 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | biomarkers, procalcitonin, c-reactive protein, monocyte distribution width, sepsis, Medicine |
| الوصف: | Objectives Monocyte distribution width (MDW) can be used for the early recognition of sepsis. The study compared the diagnostic accuracy of the MDW with two well-known sepsis biomarkers, procalcitonin (PCT) and C-reactive protein (CRP). Materials and Methods A study was conducted from July 2021 to October 2021, on 111 patients admitted to the Indus Hospital and Health Network. Patients from the ages of 1 to 90 years were enrolled if hospitalized for more than 24 hours for suspected sepsis to avoid inclusion of patients who had short-term stay in the emergency department. According to the Sequential Organ Failure Assessment score, the clinical team did the characterization of cases as with sepsis or without sepsis. SPSS version 24 was used, and the diagnostic accuracy of MDW was assessed and compared using the area under the curves (AUCs) acquired from receiver operating characteristic curves. Pearson's chi-square/Fisher's exact test (as per need) was applied to determine the association. A p-value of less than 0.05 was considered significant. Results Among 111 patients, 81 (73%) patients were labeled with sepsis and 30 (27%) were without sepsis. We have reported significantly higher MDW, PCT, and CRP levels in septic patients (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0974-2727 0974-7826 0042-1758 |
| Relation: | https://doaj.org/toc/0974-2727; https://doaj.org/toc/0974-7826 |
| DOI: | 10.1055/s-0042-1758666 |
| URL الوصول: | https://doaj.org/article/a35ae6e6f0cb490faa9009969330f6a2 |
| رقم الأكسشن: | edsdoj.35ae6e6f0cb490faa9009969330f6a2 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09742727 09747826 00421758 |
|---|---|
| DOI: | 10.1055/s-0042-1758666 |