دورية أكاديمية
Fitness cost of insecticide resistance on the life-traits of a Anopheles coluzzii population from the city of Yaoundé, Cameroon [version 2; peer review: 2 approved, 1 not approved]
العنوان: | Fitness cost of insecticide resistance on the life-traits of a Anopheles coluzzii population from the city of Yaoundé, Cameroon [version 2; peer review: 2 approved, 1 not approved] |
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المؤلفون: | Diane Leslie Nkahe, Edmond Kopya, Borel Djiappi-Tchamen, Wilson Toussile, Nadege Sonhafouo-Chiana, Sevilor Kekeunou, Remy Mimpfoundi, Parfait Awono-Ambene, Charles Sinclair Wondji, Christophe Antonio-Nkondjio |
المصدر: | Wellcome Open Research, Vol 5 (2020) |
بيانات النشر: | Wellcome, 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | Background: Pyrethroid resistance is rapidly expanding in An. gambiae s.l. populations across Sub-Saharan Africa. Yet there is still not enough information on the fitness cost of insecticide resistance . In the present study, the fitness cost of insecticide resistance on Anopheles coluzzii population from the city of Yaoundé was investigated. Methods: A resistant An. coluzzii colony was established from field collected mosquitoes resistant to both DDT and pyrethroid and selected for 12 generations with deltamethrin 0.05%. The Ngousso laboratory susceptible strain was used as control. A total of 100 females of each strain were blood fed and allowed for individual eggs laying, and then different life traits parameters such as fecundity, fertility, larval development time, emergence rate and longevity were measured. The TaqMan assay was used to screen for the presence of the L1014F and L1014S kdr mutations. Results: Field collected mosquitoes from the F0 generation had a mortality rate of 2.05% for DDT, 34.16% for permethrin and 50.23% for deltamethrin. The mortality rate of the F12 generation was 30.48% for deltamethrin, 1.25% for permethrin and 0% for DDT. The number of eggs laid per female was lower in the resistant colony compared to the susceptible (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2398-502X |
Relation: | https://wellcomeopenresearch.org/articles/5-171/v2; https://doaj.org/toc/2398-502X |
DOI: | 10.12688/wellcomeopenres.16039.2 |
URL الوصول: | https://doaj.org/article/35b5e84011e2473ca72bcf48e7af4778 |
رقم الأكسشن: | edsdoj.35b5e84011e2473ca72bcf48e7af4778 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 2398502X |
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DOI: | 10.12688/wellcomeopenres.16039.2 |