دورية أكاديمية
A high-density genetic map construction and sex-related loci identification in Chinese Giant salamander
| العنوان: | A high-density genetic map construction and sex-related loci identification in Chinese Giant salamander |
|---|---|
| المؤلفون: | Qiaomu Hu, Yang Liu, Xiaolin Liao, Haifeng Tian, Xiangshan Ji, Jiajie Zhu, Hanbing Xiao |
| المصدر: | BMC Genomics, Vol 22, Iss 1, Pp 1-8 (2021) |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biotechnology LCC:Genetics |
| مصطلحات موضوعية: | Chinese giant salamander, ddRAD, SNP, High-density linkage map, Sex-related loci mapping, Biotechnology, TP248.13-248.65, Genetics, QH426-470 |
| الوصف: | Abstract Background The Chinese giant salamander Andrias davidianus is an important amphibian species in China because of its increasing economic value, protection status and special evolutionary position from aquatic to terrestrial animal. Its large genome presents challenges to genetic research. Genetic linkage mapping is an important tool for genome assembly and determination of phenotype-related loci. Results In this study, we constructed a high-density genetic linkage map using ddRAD sequencing technology to obtain SNP genotyping data of members from an full-sib family which sex had been determined. A total of 10,896 markers were grouped and oriented into 30 linkage groups, representing 30 chromosomes of A. davidianus. The genetic length of LGs ranged from 17.61 cM (LG30) to 280.81 cM (LG1), with a mean inter-locus distance ranging from 0.11(LG3) to 0.48 cM (LG26). The total genetic map length was 2643.10 cM with an average inter-locus distance of 0.24 cM. Three sex-related loci and four sex-related markers were found on LG6 and LG23, respectively. Conclusion We constructed the first High-density genetic linkage map and identified three sex-related loci in the Chinese giant salamander. Current results are expected to be a useful tool for future genomic studies aiming at the marker-assisted breeding of the species. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1471-2164 |
| Relation: | https://doaj.org/toc/1471-2164 |
| DOI: | 10.1186/s12864-021-07550-0 |
| URL الوصول: | https://doaj.org/article/3624328a4ece428a91c20d339c9aa927 |
| رقم الأكسشن: | edsdoj.3624328a4ece428a91c20d339c9aa927 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 14712164 |
|---|---|
| DOI: | 10.1186/s12864-021-07550-0 |