دورية أكاديمية
Synthesis and Investigation of Antimicrobial and Antioxidant Activity of 3-Nitro-N- (3-chloro-2-oxo-substituted-phenyl-azetidin-1-yl)naphtho [2,1-b]furan-2-carboxamides
| العنوان: | Synthesis and Investigation of Antimicrobial and Antioxidant Activity of 3-Nitro-N- (3-chloro-2-oxo-substituted-phenyl-azetidin-1-yl)naphtho [2,1-b]furan-2-carboxamides |
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| المؤلفون: | K. Shashikala Devi, M. Ramaiah, D. L. Roopa, V. P. Vaidya |
| المصدر: | E-Journal of Chemistry, Vol 7, Iss S1, Pp S358-S362 (2010) |
| بيانات النشر: | Wiley, 2010. |
| سنة النشر: | 2010 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | Chemistry, QD1-999 |
| الوصف: | Ethyl-3-nitronaphtho[2,1-b]furan-2-carboxylate (2) has been synthesized from ethyl naphtha [2,1-b]furan-2-carboxylate (1). This nitro product on reaction with hydrazine hydrate formed 3-nitronaphtho [2,1-b] furan-2-carbohydrazide (3). Various Schiff bases 3-nitro-N1(aryl-methylene)-substituted-naphtho [2,1-b]furan-2-carbohydrazides 4(a-g) were obtained by treating hydrazide (3) with different aldehydes. These Schiff bases on reaction with chloro acetyl chloride in presence of triethylamine in dioxane yielded 3-nitro-N-(3-chloro-2-oxo-substituted-phenyl-azetidine-1-yl) naphtha [2,1-b]furan-2-carboxamides 5(a-g). All the newly synthesized compounds have been characterized by spectral and analytical studies. The Schiff bases, 4a-g and azetidione derivatives, 5a-g have been studied for antioxidant and antimicrobial activities. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0973-4945 2090-9810 |
| Relation: | https://doaj.org/toc/0973-4945; https://doaj.org/toc/2090-9810 |
| DOI: | 10.1155/2010/863547 |
| URL الوصول: | https://doaj.org/article/362ee8653f57423ea48bad114ffe8beb |
| رقم الأكسشن: | edsdoj.362ee8653f57423ea48bad114ffe8beb |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09734945 20909810 |
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| DOI: | 10.1155/2010/863547 |