دورية أكاديمية
Defining a therapeutic range for adalimumab serum concentrations in the management of pediatric noninfectious uveitis, a step towards personalized treatment
العنوان: | Defining a therapeutic range for adalimumab serum concentrations in the management of pediatric noninfectious uveitis, a step towards personalized treatment |
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المؤلفون: | Jo L. Dehoorne, Helena Groth, Emma Carlé, Ilse De Schrijver, Celine Sys, Patricia Delbeke, Elke O. Kreps, Thomas Renson, Carolien Bonroy |
المصدر: | Pediatric Rheumatology Online Journal, Vol 21, Iss 1, Pp 1-11 (2023) |
بيانات النشر: | BMC, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Pediatrics LCC:Diseases of the musculoskeletal system |
مصطلحات موضوعية: | Pediatric noninfectious uveitis, Adalimumab, Therapeutic range, Trough levels, Therapeutic drug monitoring, Pediatrics, RJ1-570, Diseases of the musculoskeletal system, RC925-935 |
الوصف: | Abstract Background Adalimumab is currently considered the most efficacious anti-TNFα agent for childhood noninfectious uveitis (NIU). The objective of this study was to define a therapeutic range for adalimumab trough levels in the treatment of childhood NIU. Methods A retrospective, observational, pilot study of 36 children with NIU aged |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1546-0096 |
Relation: | https://doaj.org/toc/1546-0096 |
DOI: | 10.1186/s12969-023-00928-2 |
URL الوصول: | https://doaj.org/article/a36938333bc7459b99d2d5631678c5ed |
رقم الأكسشن: | edsdoj.36938333bc7459b99d2d5631678c5ed |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 15460096 |
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DOI: | 10.1186/s12969-023-00928-2 |