Durable Complete Remission of a Brainstem Glioma Treated with a Combination of Bevacizumab and Cetuximab

التفاصيل البيبلوغرافية
العنوان:	Durable Complete Remission of a Brainstem Glioma Treated with a Combination of Bevacizumab and Cetuximab
المؤلفون:	Joan Manel Gasent Blesa, Sara Blasco Mollá, María Fonfría Esparcia, JoséMiguel Sempere Ortells, Miguel Peris Godoy, Adrian Munilla Das, Balbino Mancheño Magan, Mariano Provencio Pulla, Jose Luis Sanchez, Juan Bautista Laforga Canales, Vicente Alberola Candel
المصدر:	Case Reports in Oncology, Vol 5, Iss 3, Pp 676-681 (2012)
بيانات النشر:	Karger Publishers, 2012.
سنة النشر:	2012
المجموعة:	LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية:	Glioma, Durable remission, Bevacizumab, Cetuximab, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف:	Treatment of a relapsed glioma is a clinical challenge nowadays. New active treatments are required to treat these difficult diseases. Here we present a durable complete remission of a relapsed glioblastoma that has achieved a complete radiologic response with the combination of cetuximab and bevacizumab, in a third-line setting, that has offered a progression-free survival of 20 months. We consider here both potential mechanisms for the explanation of this result. First, the potential target of the cancer stem cells (CSCs) with these two antibodies, and second, the potential recruitment of the immune system to directly pursue the CSCs.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	1662-6575 00034185
Relation:	http://www.karger.com/Article/FullText/341852; https://doaj.org/toc/1662-6575
DOI:	10.1159/000341852
URL الوصول:	https://doaj.org/article/e3815badee514242a3b5fc23ae191ff7
رقم الأكسشن:	edsdoj.3815badee514242a3b5fc23ae191ff7
قاعدة البيانات:	Directory of Open Access Journals

Full Text Finder

الوصف
تدمد:	16626575 00034185
DOI:	10.1159/000341852