دورية أكاديمية
Primary Cutaneous B-Cell Lymphomas with Large Cell Morphology: A Practical Review
| العنوان: | Primary Cutaneous B-Cell Lymphomas with Large Cell Morphology: A Practical Review |
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| المؤلفون: | Andrea Ronchi, Paola Vitiello, Giuseppe D’Abbronzo, Stefano Caccavale, Giuseppe Argenziano, Antonello Sica, Roberto Alfano, Giovanni Savarese, Massimiliano Berretta, Immacolata Cozzolino, Renato Franco |
| المصدر: | International Journal of Molecular Sciences, Vol 24, Iss 7, p 6204 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | primary cutaneous lymphoma, follicle center lymphoma, diffuse large B-cell lymphoma, leg type, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Most primary cutaneous lymphomas consist of T-cell lymphomas or small cell lymphomas; however, the skin may also be affected by lymphomas with large cell morphology, as a primary or secondary localization. A minority of cases consist of primary cutaneous B-cell lymphomas (PCBCLs). PCBCLs are a heterogeneous group of rare neoplasms with an overlapping morphological and immunohistochemical picture of the different subtypes. Nevertheless, differential diagnosis in the setting of this group of neoplasms is mandatory to identify the correct therapy and prognosis, but it may be challenging since, due to the rarity of these neoplasms, they may not always be familiar to pathologists. Indeed, immunohistochemistry may not be enough to distinguish the different histotypes, which overlap in immunohistochemical features. Furthermore, the ever-increasing knowledge of the molecular features of systemic B-cell lymphomas, such as gene rearrangements with clinical significance, has led in recent years to further investigation into the molecular landscape of PCBCLs with large cell morphology. This work aimed to provide a practical diagnostic guide for pathologists dealing with primary cutaneous large B-cell lymphomas. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/24/7/6204; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms24076204 |
| URL الوصول: | https://doaj.org/article/e38eb354ac40476090bcc0883e21ff43 |
| رقم الأكسشن: | edsdoj.38eb354ac40476090bcc0883e21ff43 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms24076204 |