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Antitumor Activity and Potential Mechanism of Novel Fullerene Derivative Nanoparticles

التفاصيل البيبلوغرافية
العنوان: Antitumor Activity and Potential Mechanism of Novel Fullerene Derivative Nanoparticles
المؤلفون: Lianjie Ye, Larwubah Kollie, Xing Liu, Wei Guo, Xiangxian Ying, Jun Zhu, Shengjie Yang, Meilan Yu
المصدر: Molecules, Vol 26, Iss 11, p 3252 (2021)
بيانات النشر: MDPI AG, 2021.
سنة النشر: 2021
المجموعة: LCC:Organic chemistry
مصطلحات موضوعية: fullerene, anti-tumor, cancer, nanoparticle, nanomedicine, Organic chemistry, QD241-441
الوصف: The development of novel nanoparticles as a new generation therapeutic drug platform is an active field of chemistry and cancer research. In recent years, fullerene nanoparticles have received extensive attention due to their unique physical and chemical properties. Properly modified fullerene nanoparticles have excellent biocompatibility and significant anti-tumor activity, which makes them have broad application prospects in the field of cancer therapy. Therefore, understanding the anti-tumor mechanism of fullerene nanoparticles is of great significance for the design and development of anti-tumor drugs with low toxicity and high targeting. This review has focused on various anti-tumor mechanisms of fullerene derivatives and discusses their toxicity and their distribution in organisms. Finally, the review points out some urgent problems that need solution before fullerene derivatives as a new generation of anti-tumor nano-drug platform enter clinical research.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 26113252
1420-3049
Relation: https://www.mdpi.com/1420-3049/26/11/3252; https://doaj.org/toc/1420-3049
DOI: 10.3390/molecules26113252
URL الوصول: https://doaj.org/article/dd3970f193ef44d6bb3d3d6dc6b5a062
رقم الأكسشن: edsdoj.3970f193ef44d6bb3d3d6dc6b5a062
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:26113252
14203049
DOI:10.3390/molecules26113252