دورية أكاديمية
Optimization-Based Approaches to Control of Probabilistic Boolean Networks
| العنوان: | Optimization-Based Approaches to Control of Probabilistic Boolean Networks |
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| المؤلفون: | Koichi Kobayashi, Kunihiko Hiraishi |
| المصدر: | Algorithms, Vol 10, Iss 1, p 31 (2017) |
| بيانات النشر: | MDPI AG, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Industrial engineering. Management engineering LCC:Electronic computers. Computer science |
| مصطلحات موضوعية: | integer programming, gene regulatory network, polynomial optimization, probabilistic Boolean network, Industrial engineering. Management engineering, T55.4-60.8, Electronic computers. Computer science, QA75.5-76.95 |
| الوصف: | Control of gene regulatory networks is one of the fundamental topics in systems biology. In the last decade, control theory of Boolean networks (BNs), which is well known as a model of gene regulatory networks, has been widely studied. In this review paper, our previously proposed methods on optimal control of probabilistic Boolean networks (PBNs) are introduced. First, the outline of PBNs is explained. Next, an optimal control method using polynomial optimization is explained. The finite-time optimal control problem is reduced to a polynomial optimization problem. Furthermore, another finite-time optimal control problem, which can be reduced to an integer programming problem, is also explained. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1999-4893 |
| Relation: | http://www.mdpi.com/1999-4893/10/1/31; https://doaj.org/toc/1999-4893 |
| DOI: | 10.3390/a10010031 |
| URL الوصول: | https://doaj.org/article/39a5ad8225bb48c9aedb3c5f7b24780b |
| رقم الأكسشن: | edsdoj.39a5ad8225bb48c9aedb3c5f7b24780b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19994893 |
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| DOI: | 10.3390/a10010031 |