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Effect of anti-VEGF treatment on nonperfusion areas in ischemic retinopathy

التفاصيل البيبلوغرافية
العنوان: Effect of anti-VEGF treatment on nonperfusion areas in ischemic retinopathy
المؤلفون: Zi-Yi Zhu, Yong-An Meng, Bin Yan, Jing Luo
المصدر: International Journal of Ophthalmology, Vol 14, Iss 11, Pp 1647-1652 (2021)
بيانات النشر: Press of International Journal of Ophthalmology (IJO PRESS), 2021.
سنة النشر: 2021
المجموعة: LCC:Ophthalmology
مصطلحات موضوعية: anti-vascular endothelial growth factor, retinal nonperfusion areas, ischemic retinopathy, macular ischemia, Ophthalmology, RE1-994
الوصف: In recent years, retinal ischemia such as that which occurs in diabetic retinopathy (DR) and retinal vein occlusion (RVO) has become a hotspot of ischemic retinopathy research. High levels of vascular endothelial growth factor (VEGF) are recognized as a major cause of macular edema (ME) in DR and RVO. High concentrations of VEGF in the vitreous can lead to serious retinal ischemia and hypoxia and form retinal nonperfusion areas (NPAs). Different levels of retinal ischemia can represent disease severity and progression. Anti-VEGF therapy as the first-line treatment for ME has been found to be effective in improving vision, but there are still disputes about whether anti-VEGF therapy could improve retinal ischemia and achieve reperfusion of previously developed retinal NPAs. Here, we review and summarize studies of the effects of anti-VEGF drugs on retinal ischemia, especially NPAs.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2222-3959
2227-4898
Relation: http://ies.ijo.cn/en_publish/2021/11/20211101.pdf; https://doaj.org/toc/2222-3959; https://doaj.org/toc/2227-4898
DOI: 10.18240/ijo.2021.11.01
URL الوصول: https://doaj.org/article/3a56299380824aa8847232d939303628
رقم الأكسشن: edsdoj.3a56299380824aa8847232d939303628
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22223959
22274898
DOI:10.18240/ijo.2021.11.01