دورية أكاديمية
Peritoneal dialysis modality transition and impact on phosphate and potassium serum levels
| العنوان: | Peritoneal dialysis modality transition and impact on phosphate and potassium serum levels |
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| المؤلفون: | Daniela Peruzzo, Murilo Guedes, John W. Larkin, Guilherme Yokoyama, Taynara Lopes dos Santos, Roberto Pecoits-Filho, Silvia Carreira Ribeiro, Alfonso Ramos, Pasqual Barretti, Thyago Proença de Moraes, on behalf of the BRAZPD Investigators |
| المصدر: | PLoS ONE, Vol 16, Iss 10 (2021) |
| بيانات النشر: | Public Library of Science (PLoS), 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Peritoneal dialysis (PD) modalities affect solute removal differently. However, the impacts of switching PD modalities on serum levels of biomarkers of different sizes are not known. Our objective was to analyze whether a change in the PD modality associates with the levels of two routine biochemical laboratories. In this multicentric prospective cohort study. we selected all patients who remained on a PD modality for at least 6 months and switched PD modality. Patients were also required to be treated with the same PD modality for at least 3 months before and after the modality change. The primary outcome was change in potassium and phosphate serum levels. We identified 737 eligible patients who switched their PD modality during the study. We found mean serum phosphate levels increased during the 3 months after switching from CAPD to APD and conversely decreased after switching to from APD to CAPD. In contrast, for potassium the difference in the mean serum levels was comparable between groups switching from CAPD to APD, and vice versa. In conclusion, CAPD seems to be as efficient as APD for the control of potassium serum levels, but more effective for the control of phosphate serum levels. The effect of a higher removal of middle size molecules as result of PD modalities in terms of clinical and patient-reported outcomes should be further explored. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| Relation: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519456/?tool=EBI; https://doaj.org/toc/1932-6203 |
| URL الوصول: | https://doaj.org/article/3a9f805efce64f4aa5b2ef534815d406 |
| رقم الأكسشن: | edsdoj.3a9f805efce64f4aa5b2ef534815d406 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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