The molecular and functional landscape of resistance to immune checkpoint blockade in melanoma

التفاصيل البيبلوغرافية
العنوان:	The molecular and functional landscape of resistance to immune checkpoint blockade in melanoma
المؤلفون:	Su Yin Lim, Elena Shklovskaya, Jenny H. Lee, Bernadette Pedersen, Ashleigh Stewart, Zizhen Ming, Mal Irvine, Brindha Shivalingam, Robyn P. M. Saw, Alexander M. Menzies, Matteo S. Carlino, Richard A. Scolyer, Georgina V. Long, Helen Rizos
المصدر:	Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
بيانات النشر:	Nature Portfolio, 2023.
سنة النشر:	2023
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Immunotherapy resistance is common among melanoma patients. Here, the authors identify three resistance mechanism subtypes across tumor-derived cell lines and matched samples and highlight antigen presentation disruption as a key mediator of resistance.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-023-36979-y
URL الوصول:	https://doaj.org/article/3b0749adf7cc4ff997d621256e99d21e
رقم الأكسشن:	edsdoj.3b0749adf7cc4ff997d621256e99d21e
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-023-36979-y