دورية أكاديمية

Could uric acid to high density lipoprotein-cholesterol ratio be considered as a marker of hemodialysis sufficiency?

التفاصيل البيبلوغرافية
العنوان: Could uric acid to high density lipoprotein-cholesterol ratio be considered as a marker of hemodialysis sufficiency?
المؤلفون: Orhan Coşkun, Mustafa Çapraz
المصدر: Journal of Contemporary Medicine, Vol 13, Iss 1, Pp 86-91 (2023)
بيانات النشر: Rabia Yılmaz, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
مصطلحات موضوعية: hemodiyaliz, ürik asit hdl oranı, üre düşüş oranı, hemodialysis, uric acid to hdl cholesterol ratio, urea reduction ratio, Medicine
الوصف: Aim: Hemodialysis (HD) is one of the most widely utilized renal replacement therapies in individuals with end-stage chronic kidney disease (CKD). The purpose of this study was to compare the Uric acid to HDL cholesterol ratio (UHR) levels of well-treated HD patients to those of those who had inadequate HD therapy. Materials and Methods: Data on HD patients were acquired from patient files and the institution's database. A URR value of more than 70% designated the sufficient HD group, whereas less than 70% defined the insufficient HD group. Furthermore, laboratory data, such as the UHR of the study groups, were compared. Results: The UHRs for adequate and inadequate HD were 0.160±04 and 0.20±0.07, respectively. The UHR of patients with insufficient HD was substantially greater than that of the subjects with sufficient HD (p=0.004). Besides, UHR was substantially and positively connected with urea before HD (r=0.37, p=0.001), urea after HD (r=0.39, p=0.001), serum creatinine before HD (r=0.48, p0.001), serum creatinine after HD (r=0.45, p0.001), and negatively correlated with URR (r=-0.29, p=0.008), according to correlation analyses. In individuals with chronic renal disease, a UHR value higher than 0.16 exhibited 67% sensitivity and 57% specificity in detecting inadequate HD. Conclusion: We propose that UHR, in addition to URR, might be used to determine HS sufficiency in CKD patients undergoing HD therapy.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Turkish
تدمد: 2667-7180
Relation: https://dergipark.org.tr/tr/download/article-file/2850039; https://doaj.org/toc/2667-7180
DOI: 10.16899/jcm.1223641
URL الوصول: https://doaj.org/article/3b1551ddbd2a4ce99f1dc00bc0646da3
رقم الأكسشن: edsdoj.3b1551ddbd2a4ce99f1dc00bc0646da3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:26677180
DOI:10.16899/jcm.1223641