دورية أكاديمية
The prophylactic effects of gabapentin on postoperative sore throat after thyroid surgery
| العنوان: | The prophylactic effects of gabapentin on postoperative sore throat after thyroid surgery |
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| المؤلفون: | Jae Ho Lee, Hyun Kyu Lee, Na Hyung Chun, Yoon So, Chi Young Lim |
| المصدر: | Korean Journal of Anesthesiology, Vol 64, Iss 2, Pp 138-142 (2013) |
| بيانات النشر: | Korean Society of Anesthesiologists, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Anesthesiology |
| مصطلحات موضوعية: | gabapentin, postoperative pharyngitis, thyroid cancer, Anesthesiology, RD78.3-87.3 |
| الوصف: | BackgroundPostoperative sore throat (POST) is considered a usual complication after tracheal intubation, especially, thyroid surgery. Gabapentin is a widely studied multimodal perioperative drug, which can be used to treat acute postoperative pain. The primary endpoints of this study was a reduction of the incidence of POST at rest and during the swallowing movements after thyroid surgery. And the second endpoints was a reduction of the intensity of the POST after thyroid surgery.MethodsSeventy-one patients that underwent elective thyroid surgery received either gabapentin (Neurontin™ 600 mg) or placebo, orally, one hour before anesthesia. The VAS scores and incidences of POST and adverse effects were determined at 1 hr, 6 hr, 12 hr, and 24 hr after surgery at rest and during swallowing movement.ResultsThe gabapentin group (N = 36) showed a lower incidence of POST than the placebo group (N = 35) (47% vs. 78%, P = 0.038), and had significant lower VAS score at 6 and 24 hours after surgery in the resting state. However, during the movement, no intergroup differences were found in terms of the incidence of POST (83% vs. 91%, P = 0.305) or VAS score. Furthermore, no significant difference was observed between the two groups, in adverse effects.ConclusionsGabapentin (Neurontin™ 600 mg) administered 1 hr before anesthesia reduced the intensity and incidence of POST during the resting state without a significant adverse event, during the 24 hr after thyroid surgery. However, gabapentin did not reduce the intensity and incidence of POST during the swallowing movement. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2005-6419 2005-7563 |
| Relation: | http://ekja.org/upload/pdf/kjae-64-138.pdf; https://doaj.org/toc/2005-6419; https://doaj.org/toc/2005-7563 |
| DOI: | 10.4097/kjae.2013.64.2.138 |
| URL الوصول: | https://doaj.org/article/ddd3b7f417834e4b9d22c242f45efc15 |
| رقم الأكسشن: | edsdoj.3b7f417834e4b9d22c242f45efc15 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20056419 20057563 |
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| DOI: | 10.4097/kjae.2013.64.2.138 |