دورية أكاديمية
EFFEKTIVNOST' VNUTRISUSTAVNOGO VVEDENIYa GENTAMITsINA PRI PODAGRIChESKOM ARTRITE
العنوان: | EFFEKTIVNOST' VNUTRISUSTAVNOGO VVEDENIYa GENTAMITsINA PRI PODAGRIChESKOM ARTRITE |
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المؤلفون: | A. V. Orlov-Morozov, E A Dolzikova, E A Orlova-Morozova, N G Berdnikova, T Ya Selezneva, E V Tkachenko, R I Elagin |
المصدر: | Научно-практическая ревматология, Vol 38, Iss 2, Pp 22-27 (2000) |
بيانات النشر: | IMA PRESS LLC, 2000. |
سنة النشر: | 2000 |
المجموعة: | LCC:Diseases of the musculoskeletal system |
مصطلحات موضوعية: | gout arthritis, gentamycin, intaarticular injections, Diseases of the musculoskeletal system, RC925-935 |
الوصف: | Aim: То determine the efficacy of intraarticular injections of Gentamycin in gout arthtiris a randomized double blind, placebo-controlled trial was carried out. Material and methods: 27 patients answering the criteria of the definite gout diagnosis were randomly recruited from rheumatological clinic. The patients received an intraarticular injection of either 4- mg of Gentamycin in 4 ml of sterile 0.25% procaine or 5 ml of the vehicle alone. Results: It was found that weekly intraarticular injections of Gentamycin performed better than the inert vehicle alone over a 2-week period and were conjirmed during 4 week period of crossing-over. Conclusion: The possible mechanisms of Gentamycin activity are discussed. It is concluded, that intraarticular administration of Gentamicin offers signijicant benejit over placebo. The serious side effects were not obsen’ed. Therefore, the technique could be applied in the routine treatment of gout. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | Russian |
تدمد: | 1995-4484 1995-4492 |
Relation: | https://rsp.mediar-press.net/rsp/article/view/1135; https://doaj.org/toc/1995-4484; https://doaj.org/toc/1995-4492 |
DOI: | 10.14412/1995-4484-2000-1229 |
URL الوصول: | https://doaj.org/article/3b8480aaede246bc83a043fb96da6d4e |
رقم الأكسشن: | edsdoj.3b8480aaede246bc83a043fb96da6d4e |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19954484 19954492 |
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DOI: | 10.14412/1995-4484-2000-1229 |