دورية أكاديمية

Bariatric surgery in liver cirrhosis

التفاصيل البيبلوغرافية
العنوان: Bariatric surgery in liver cirrhosis
المؤلفون: A. S. Mehdorn, Y. Moulla, M. Mehdorn, A. Dietrich, W. Schönfels, T. Becker, F. Braun, J. H. Beckmann, M. Linecker
المصدر: Frontiers in Surgery, Vol 9 (2022)
بيانات النشر: Frontiers Media S.A., 2022.
سنة النشر: 2022
المجموعة: LCC:Surgery
مصطلحات موضوعية: bariatric surgery, sleeve gastrectomy, obesity, obese patients, liver cirrhosis, NAFLD, Surgery, RD1-811
الوصف: IntroductionObesity is frequently associated with its hepatic manifestation, the nonalcoholic fatty liver disease (NAFLD). The most effective treatment for morbid obesity is bariatric surgery (BS) also improving NAFLD and liver function. In patients where NAFLD has already progressed to liver cirrhosis, BS can be considered a high-risk procedure. Hence, consideration of the procedure and the most appropriate timing is crucial.Material and MethodsObese patients suffering from NAFLD who underwent BS from two German University Medical Centers were retrospectively analyzed.ResultsTwenty-seven patients underwent BS. Most common procedures were laparoscopic Roux-en-Y-gastric (RYGB) and laparoscopic sleeve gastrectomy (SG). All patients suffered from liver cirrhosis Child A. A preoperative transjugular portosystemic shunt (TIPS) was established in three patients and failed in another patient. Postoperative complications consisted of wound healing disorders (n = 2), anastomotic bleeding (n = 1), and leak from the staple line (n = 1). This patient suffered from intraoperatively detected macroscopic liver cirrhosis. Excess weight loss was 73% and 85% after 1 and 2 years, respectively. Two patients suffered from postoperative aggravation of their liver function, resulting in a higher Child–Pugh score, while three could be removed from the waiting list for a liver transplantation.ConclusionBS leads to weight loss, both after SG and RYGB, and potential improvement of liver function in liver cirrhosis. These patients need to be considered with care when evaluated for BS. Preoperative TIPS implantation may reduce the perioperative risk in selected patients.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2296-875X
Relation: https://www.frontiersin.org/articles/10.3389/fsurg.2022.986297/full; https://doaj.org/toc/2296-875X
DOI: 10.3389/fsurg.2022.986297
URL الوصول: https://doaj.org/article/ddca3c6b89d247dfa5172f4df6577adb
رقم الأكسشن: edsdoj.3c6b89d247dfa5172f4df6577adb
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:2296875X
DOI:10.3389/fsurg.2022.986297