دورية أكاديمية
Combined hyperthermia and radiotherapy for prostate cancer: a systematic review
| العنوان: | Combined hyperthermia and radiotherapy for prostate cancer: a systematic review |
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| المؤلفون: | Jennifer Le Guevelou, Monica Emilia Chirila, Vérane Achard, Pauline Coralie Guillemin, Orane Lorton, Johannes W. E. Uiterwijk, Giovanna Dipasquale, Rares Salomir, Thomas Zilli |
| المصدر: | International Journal of Hyperthermia, Vol 39, Iss 1, Pp 547-556 (2022) |
| بيانات النشر: | Taylor & Francis Group, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medical technology |
| مصطلحات موضوعية: | Prostate cancer, radiotherapy, hyperthermia, toxicity, recurrence, Medical technology, R855-855.5 |
| الوصف: | Optimization of treatment strategies for prostate cancer patients treated with curative radiation therapy (RT) represents one of the major challenges for the radiation oncologist. Dose escalation or combination of RT with systemic therapies is used to improve tumor control in patients with unfavorable prostate cancer, at the risk of increasing rates and severity of treatment-related toxicities. Elevation of temperature to a supra-physiological level has been shown to both increase tumor oxygenation and reduce DNA repair capabilities. Thus, hyperthermia (HT) combined with RT represents a compelling treatment strategy to improve the therapeutic ratio in prostate cancer patients. The aim of the present systematic review is to report on preclinical and clinical evidence supporting the combination of HT and RT for prostate cancer, discussing future applications and developments of this combined treatment. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 02656736 1464-5157 0265-6736 |
| Relation: | https://doaj.org/toc/0265-6736; https://doaj.org/toc/1464-5157 |
| DOI: | 10.1080/02656736.2022.2053212 |
| URL الوصول: | https://doaj.org/article/c3cff2b0c4e2426ebd5345735c2f191b |
| رقم الأكسشن: | edsdoj.3cff2b0c4e2426ebd5345735c2f191b |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 02656736 14645157 |
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| DOI: | 10.1080/02656736.2022.2053212 |