دورية أكاديمية
Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa
العنوان: | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa |
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المؤلفون: | Tao Li, Yingjie Song, Liming Luo, Ninglin Zhao, Lihui He, Mei Kang, Changcheng Li, Yibo Zhu, Yalin Shen, Chang Zhao, Jing Yang, Qin Huang, Xingyu Mou, Zhiyong Zong, Jinliang Yang, Hong Tang, Yongxing He, Rui Bao |
المصدر: | mBio, Vol 12, Iss 1 (2021) |
بيانات النشر: | American Society for Microbiology, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Microbiology |
مصطلحات موضوعية: | Microbiology, QR1-502 |
الوصف: | HtrA-family proteases are commonly employed to sense the protein folding stress and activate the regulated intramembrane proteolysis (RIP) cascade in Gram-negative bacteria. Here, we reveal the unique dual-signal activation and dynamic regulation properties of AlgW, an HtrA-type protease triggering the AlgU stress-response pathway, which controls alginate production and mucoid conversion in Pseudomonas aeruginosa |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2161-2129 2150-7511 |
Relation: | https://doaj.org/toc/2161-2129; https://doaj.org/toc/2150-7511 |
DOI: | 10.1128/mBio.03299-20 |
URL الوصول: | https://doaj.org/article/3d364595942a4765b601a32837d729aa |
رقم الأكسشن: | edsdoj.3d364595942a4765b601a32837d729aa |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 21612129 21507511 |
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DOI: | 10.1128/mBio.03299-20 |