دورية أكاديمية
Associations of tissue factor and tissue factor pathway inhibitor with organ dysfunctions in septic shock
العنوان: | Associations of tissue factor and tissue factor pathway inhibitor with organ dysfunctions in septic shock |
---|---|
المؤلفون: | Georg Franz Lehner, Anna Katharina Tobiasch, Fabian Perschinka, Timo Mayerhöfer, Markus Waditzer, Viktoria Haller, Birgit Zassler, Sarah Maier, Hanno Ulmer, Michael Joannidis |
المصدر: | Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024) |
بيانات النشر: | Nature Portfolio, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Sepsis, Septic shock, Coagulation, Tissue factor, Tissue factor pathway inhibitor, Microvasculature, Medicine, Science |
الوصف: | Abstract Coagulopathy, microvascular alterations and concomitant organ dysfunctions are hallmarks of sepsis. Attempts to attenuate coagulation activation with an inhibitor of tissue factor (TF), i.e. tissue factor pathway inhibitor (TFPI), revealed no survival benefit in a heterogenous group of sepsis patients, but a potential survival benefit in patients with an international normalized ratio (INR) |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2045-2322 |
Relation: | https://doaj.org/toc/2045-2322 |
DOI: | 10.1038/s41598-024-65262-3 |
URL الوصول: | https://doaj.org/article/3dc6b90540944134818d2c383b64e312 |
رقم الأكسشن: | edsdoj.3dc6b90540944134818d2c383b64e312 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20452322 |
---|---|
DOI: | 10.1038/s41598-024-65262-3 |