دورية أكاديمية

A review of becaplermin gel in the treatment of diabetic neuropathic foot ulcers

التفاصيل البيبلوغرافية
العنوان: A review of becaplermin gel in the treatment of diabetic neuropathic foot ulcers
المؤلفون: Robert C Fang, Robert D Galiano
المصدر: Biologics: Targets & Therapy, Vol 2008, Iss Issue 1, Pp 1-12 (2008)
بيانات النشر: Dove Medical Press, 2008.
سنة النشر: 2008
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: Medicine (General), R5-920
الوصف: Robert C Fang, Robert D GalianoDivision of Plastic and Reconstructive Surgery and Wound Healing Research Laboratory, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USAAbstract: Diabetic neuropathic foot ulcers represent a serious health care burden to patients and to society. While the management of chronic diabetic foot ulcers has improved in recent years, it remains a frustrating problem for a variety of clinicians. This review examines the scientific underpinnings supporting the use of becaplermin (Regranex®; Ortho-McNeil Pharmaceutical, Raritan, NJ), or recombinant human platelet-derived growth factor (rhPDGF-BB), in diabetic forefoot wounds. An emphasis is placed upon proper medical and surgical care of diabetic foot wounds, as multiple studies have demonstrated that the success of this growth factor in accelerating healing is ultimately dependent on proper ulcer care. A focus on the cost-effectiveness of this form of therapy in the treatment of diabetic foot ulcers is also outlined.Keywords: becaplermin, diabetes, foot ulcer, growth factor
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1177-5475
1177-5491
Relation: http://www.dovepress.com/a-review-of-becaplermin-gel-in-the-treatment-of-diabetic-neuropathic-f-a49; https://doaj.org/toc/1177-5475; https://doaj.org/toc/1177-5491
URL الوصول: https://doaj.org/article/3e053306c47a418ab47b4587e015c902
رقم الأكسشن: edsdoj.3e053306c47a418ab47b4587e015c902
قاعدة البيانات: Directory of Open Access Journals