دورية أكاديمية
A review of becaplermin gel in the treatment of diabetic neuropathic foot ulcers
العنوان: | A review of becaplermin gel in the treatment of diabetic neuropathic foot ulcers |
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المؤلفون: | Robert C Fang, Robert D Galiano |
المصدر: | Biologics: Targets & Therapy, Vol 2008, Iss Issue 1, Pp 1-12 (2008) |
بيانات النشر: | Dove Medical Press, 2008. |
سنة النشر: | 2008 |
المجموعة: | LCC:Medicine (General) |
مصطلحات موضوعية: | Medicine (General), R5-920 |
الوصف: | Robert C Fang, Robert D GalianoDivision of Plastic and Reconstructive Surgery and Wound Healing Research Laboratory, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USAAbstract: Diabetic neuropathic foot ulcers represent a serious health care burden to patients and to society. While the management of chronic diabetic foot ulcers has improved in recent years, it remains a frustrating problem for a variety of clinicians. This review examines the scientific underpinnings supporting the use of becaplermin (Regranex®; Ortho-McNeil Pharmaceutical, Raritan, NJ), or recombinant human platelet-derived growth factor (rhPDGF-BB), in diabetic forefoot wounds. An emphasis is placed upon proper medical and surgical care of diabetic foot wounds, as multiple studies have demonstrated that the success of this growth factor in accelerating healing is ultimately dependent on proper ulcer care. A focus on the cost-effectiveness of this form of therapy in the treatment of diabetic foot ulcers is also outlined.Keywords: becaplermin, diabetes, foot ulcer, growth factor |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1177-5475 1177-5491 |
Relation: | http://www.dovepress.com/a-review-of-becaplermin-gel-in-the-treatment-of-diabetic-neuropathic-f-a49; https://doaj.org/toc/1177-5475; https://doaj.org/toc/1177-5491 |
URL الوصول: | https://doaj.org/article/3e053306c47a418ab47b4587e015c902 |
رقم الأكسشن: | edsdoj.3e053306c47a418ab47b4587e015c902 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 11775475 11775491 |
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