دورية أكاديمية
Positron Emission-Computed Tomography, Cryobiopsy versus Bronchoalveolar Lavage and Computed Tomography Findings for Interstitial Lung Disease: A Long-Term Follow-Up
العنوان: | Positron Emission-Computed Tomography, Cryobiopsy versus Bronchoalveolar Lavage and Computed Tomography Findings for Interstitial Lung Disease: A Long-Term Follow-Up |
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المؤلفون: | Paul Zarogoulidis, Dimitris Matthaios, Haidong Huang, Chong Bai, Wolfgang Hohenforst-Schmidt, Konstantinos Porpodis, Dimitris Petridis, Konstantinos Pigakis, Nikolaos Kougkas, Panagoula Oikonomou, Christina Nikolaou, Dimitris Hatzibougias, Chrysanthi Sardeli |
المصدر: | Medicina, Vol 59, Iss 4, p 787 (2023) |
بيانات النشر: | MDPI AG, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Medicine (General) |
مصطلحات موضوعية: | cryobiopsy, ILD, computed tomography scan, positron emission-computed tomography, bronchoscopy, Medicine (General), R5-920 |
الوصف: | Background and Objectives: Interstitial lung diseases have always been an issue for pulmonary and rheumatology physicians. Computed tomography scans with a high-resolution protocol and bronchoalveolar lavage have been used along with biochemical blood tests to reach a diagnosis. Materials and Methods: We included 80 patients in total. First, all patients had their diagnosis with computed tomography of the thorax, serological/ immunological blood tests and bronchoalveolar lavage. However; after 3 months, all were divided into 2 groups: those who had bronchoalveolar lavage again and those who had cryobiopsy instead of bronchoalveolar lavage (40/40). Positron emission-computed tomography was also performed upon the first and second diagnosis. The patients’ follow-up was 4 years from diagnosis. Results: Patients suffered most from chronic obstructive pulmonary disease (56, 70%), while lung cancer was rarely encountered in the sample (7, 9.75%). Age distribution ranged between 53 and 68 years with a mean value of 60 years. The computed tomography findings revealed 25 patients with typical diagnosis (35.2%), 17 with interstitial pulmonary fibrosis (23.9%) and 11 with probable diagnosis (11%). The cryobiopsy technique led to a new diagnosis in 28 patients (35% of the total sample). Patients who had a new diagnosis with cryobiopsy had a mean survival time of 710 days (Conclusions: Cryobiopsy is a safe tool for patients with interstitial lung disease and can assist in the diagnosis of interstitial lung diseases. The survival of patients was increased in the cryobiopsy group versus only bronchoalveolar lavage for disease diagnosis. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1648-9144 1010-660X |
Relation: | https://www.mdpi.com/1648-9144/59/4/787; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144 |
DOI: | 10.3390/medicina59040787 |
URL الوصول: | https://doaj.org/article/a3e64ee0e8f34246b49ad97e17b76d1a |
رقم الأكسشن: | edsdoj.3e64ee0e8f34246b49ad97e17b76d1a |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 16489144 1010660X |
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DOI: | 10.3390/medicina59040787 |