دورية أكاديمية
Evaluation of Haemophilus influenzaetype b carrier status among children 10 years after the introduction of Hib vaccine in Brazil
| العنوان: | Evaluation of Haemophilus influenzaetype b carrier status among children 10 years after the introduction of Hib vaccine in Brazil |
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| المؤلفون: | Rosemeire Cobo Zanella, Maria Cristina de Cunto Brandileone, Ana Lúcia Andrade, Cinthya Terumi Ogassavara, Cleiton Eduardo Fiório, Angela Pires Brandão, Samanta Cristine Grassi Almeida, Ana Paula Silva Lemos, Maria Cecília Gorla, Telma Regina Carvalhanas, Helena Sato, Bernadete Liphaus, Maria Lígia Nerger, Monica Conde, Ana Freitas Ribeiro |
| المصدر: | Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 6, Pp 755-759 (2015) |
| بيانات النشر: | Fundação Oswaldo Cruz (FIOCRUZ), 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Microbiology LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Haemophilus influenzae, type b, nasopharyngeal carriage, Hib conjugate vaccine, Brazil, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216 |
| الوصف: | The aim of the present study was to assess the prevalence of Haemophilus influenzaetype b (Hib) nasopharyngeal (NP) colonisation among healthy children where Hib vaccination using a 3p+0 dosing schedule has been routinely administered for 10 years with sustained coverage (> 90%). NP swabs were collected from 2,558 children who had received the Hib vaccine, of whom 1,379 were 12-< 24 months (m) old and 1,179 were 48-< 60 m old. Hi strains were identified by molecular methods. Hi carriage prevalence was 45.1% (1,153/2,558) and the prevalence in the 12-< 24 m and 48-< 60 m age groups were 37.5% (517/1,379) and 53.9% (636/1,179), respectively. Hib was identified in 0.6% (16/2,558) of all children in the study, being 0.8% (11/1,379) and 0.4% (5/1,179) among the 12-< 24 m and 48-< 60 m age groups, respectively. The nonencapsulate Hi colonisation was 43% (n = 1,099) and was significantly more frequent at 48-< 60 m of age (51.6%, n = 608) compared with that at 12-< 24 m of age (35.6%, n = 491). The overall resistance rates to ampicillin and chloramphenicol were 16.5% and 3.7%, respectively; the co-resistance was detected in 2.6%. Our findings showed that the Hib carrier rate in healthy children under five years was very low after 10 years of the introduction of the Hib vaccine. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-8060 0074-0276 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000600755&lng=en&tlng=en; https://doaj.org/toc/1678-8060 |
| DOI: | 10.1590/0074-02760150140 |
| URL الوصول: | https://doaj.org/article/a3f248288e8e42718e4bfc6b11e87d5a |
| رقم الأكسشن: | edsdoj.3f248288e8e42718e4bfc6b11e87d5a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16788060 00740276 |
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| DOI: | 10.1590/0074-02760150140 |