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A Population-Based Cohort Study on Peripheral Arterial Disease in Patients with Schizophrenia.

التفاصيل البيبلوغرافية
العنوان: A Population-Based Cohort Study on Peripheral Arterial Disease in Patients with Schizophrenia.
المؤلفون: Wen-Yu Hsu, Cheng-Li Lin, Chia-Hung Kao
المصدر: PLoS ONE, Vol 11, Iss 2, p e0148759 (2016)
بيانات النشر: Public Library of Science (PLoS), 2016.
سنة النشر: 2016
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Peripheral arterial disease (PAD) is considered the leading cause of atherosclerotic cardiovascular morbidity. Several risk factors of PAD have been observed in patients with schizophrenia. Therefore, we hypothesize that the incidence of PAD is higher in the schizophrenia population than in the general population.The patients in this population-based cohort study were selected from the Taiwanese National Health Insurance Research Database on the basis of the claims data from 2000 to 2011. We compared the incidence of PAD between schizophrenia and nonschizophrenia cohorts. Cox proportional hazard regression models were employed for analyzing the risk of PAD after adjustment for sex, age, and comorbidities.The adjusted hazard ratio (HR) for PAD in the schizophrenia cohort was 1.26-fold higher than that in the nonschizophrenia cohort. Furthermore, patients with schizophrenia using atypical antipsychotics exhibited a high adjusted HR for PAD.Compared with the general population, the risk of PAD is higher among patients with schizophrenia. Early diagnosis and intervention can mitigate complications resulting from cardiovascular diseases and lower mortality.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC4752502?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0148759
URL الوصول: https://doaj.org/article/3f49c17172434eb987dbe9f7c0fbfd9d
رقم الأكسشن: edsdoj.3f49c17172434eb987dbe9f7c0fbfd9d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0148759