Hyperspectral image (HSI) classification is an important research topic in detailed analysis of the Earth’s surface. However, the performance of the classification is often hampered by the high-dimensionality features and limited training samples of the HSIs which has fostered research about semi-supervised learning (SSL). In this paper, we propose a shape adaptive neighborhood information (SANI) based SSL (SANI-SSL) method that takes full advantage of the adaptive spatial information to select valuable unlabeled samples in order to improve the classification ability. The improvement of the classification mainly relies on two aspects: (1) the improvement of the feature discriminability, which is accomplished by exploiting spectral-spatial information, and (2) the improvement of the training samples’ representativeness which is accomplished by exploiting the SANI for both labeled and unlabeled samples. First, the SANI of labeled samples is extracted, and the breaking ties (BT) method is used in order to select valuable unlabeled samples from the labeled samples’ neighborhood. Second, the SANI of unlabeled samples are also used to find more valuable samples, with the classifier combination method being used as a strategy to ensure confidence and the adaptive interval method used as a strategy to ensure informativeness. The experimental comparison results tested on three benchmark HSI datasets have demonstrated the significantly superior performance of our proposed method.