دورية أكاديمية
Lung volume recruitment acutely increases respiratory system compliance in individuals with severe respiratory muscle weakness
العنوان: | Lung volume recruitment acutely increases respiratory system compliance in individuals with severe respiratory muscle weakness |
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المؤلفون: | Yannick Molgat-Seon, Liam M. Hannan, Paolo B. Dominelli, Carli M. Peters, Renee J. Fougere, Douglas A. McKim, A. William Sheel, Jeremy D. Road |
المصدر: | ERJ Open Research, Vol 3, Iss 1 (2017) |
بيانات النشر: | European Respiratory Society, 2017. |
سنة النشر: | 2017 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | Medicine |
الوصف: | The aim of the present study was to determine whether lung volume recruitment (LVR) acutely increases respiratory system compliance (Crs) in individuals with severe respiratory muscle weakness (RMW). Individuals with RMW resulting from neuromuscular disease or quadriplegia (n=12) and healthy controls (n=12) underwent pulmonary function testing and the measurement of Crs at baseline, immediately after, 1 h after and 2 h after a single standardised session of LVR. The LVR session involved 10 consecutive supramaximal lung inflations with a manual resuscitation bag to the highest tolerable mouth pressure or a maximum of 50 cmH2O. Each LVR inflation was followed by brief breath-hold and a maximal expiration to residual volume. At baseline, individuals with RMW had lower Crs than controls (37±5 cmH2O versus 109±10 mL·cmH2O−1, p0.05). LVR had no significant effect on measures of pulmonary function at any time point in either group (all p>0.05). During inflations, mean arterial pressure decreased significantly relative to baseline by 10.4±2.8 mmHg and 17.3±3.0 mmHg in individuals with RMW and controls, respectively (both p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2312-0541 23120541 |
Relation: | http://openres.ersjournals.com/content/3/1/00135-2016.full; https://doaj.org/toc/2312-0541 |
DOI: | 10.1183/23120541.00135-2016 |
URL الوصول: | https://doaj.org/article/3fe6a3eec002403ca871c1cde63fd16d |
رقم الأكسشن: | edsdoj.3fe6a3eec002403ca871c1cde63fd16d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 23120541 |
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DOI: | 10.1183/23120541.00135-2016 |