دورية أكاديمية
Factors influencing platelet isolation: a prospective multicenter study from Western China
العنوان: | Factors influencing platelet isolation: a prospective multicenter study from Western China |
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المؤلفون: | Shan Liu, Guishu Yang, Guangqun Zeng, Xihao Zhou, Rong Chen, Bin Chen, Jin Chen, Xiaoxia Wen, Xingmei Zhang, Hanxiao Ren, Ruiling Zu, Dongsheng Wang, Ping Leng, Huaichao Luo |
المصدر: | Platelets, Vol 34, Iss 1 (2023) |
بيانات النشر: | Taylor & Francis Group, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Diseases of the blood and blood-forming organs |
مصطلحات موضوعية: | biomarker, liquid biopsy, multicenter study, platelet isolation, platelet recovery rate (prr), tumor-educated platelets (teps), Diseases of the blood and blood-forming organs, RC633-647.5 |
الوصف: | Tumor-educated platelets (TEPs) have been widely reported to have promising application potential; nonetheless, platelet isolation from peripheral blood is an important but neglected step in TEPs research for platelet-based liquid biopsy. In this article, we discussed some common influence factors for platelet isolation. To investigate the factors involved in platelet isolation, a prospective multicenter study was conducted on healthy Han Chinese adults (18 to 79 years of age). A total of 208 individuals were included in the final statistical analysis out of the 226 healthy volunteers who were prospectively enrolled from four hospitals. The primary study metric was the platelet recovery rate (PRR). The similar pattern was observed in the four hospitals, The PRR at room temperature (23°C±2°C) was slightly higher than the PRR at cold temperature (4°C±2°C). Moreover, the PRR gradually decreased as the storage time increased. The PRR for samples within 2 hours of storage is significantly higher than for samples beyond 2 hours (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0953-7104 1369-1635 09537104 |
Relation: | https://doaj.org/toc/0953-7104; https://doaj.org/toc/1369-1635 |
DOI: | 10.1080/09537104.2023.2194445 |
URL الوصول: | https://doaj.org/article/acc40135342841eebf21d2dac334edf3 |
رقم الأكسشن: | edsdoj.40135342841eebf21d2dac334edf3 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 09537104 13691635 |
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DOI: | 10.1080/09537104.2023.2194445 |