دورية أكاديمية
3.7 ARTERIAL STIFFNESS FOR THE EARLY PREDICTION OF PRE-ECLAMPSIA COMPARED WITH CLINICAL CHARACTERISTICS, UTERINE ARTERY DOPPLER INDICES, AND ANGIOGENIC BIOMARKERS
| العنوان: | 3.7 ARTERIAL STIFFNESS FOR THE EARLY PREDICTION OF PRE-ECLAMPSIA COMPARED WITH CLINICAL CHARACTERISTICS, UTERINE ARTERY DOPPLER INDICES, AND ANGIOGENIC BIOMARKERS |
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| المؤلفون: | Kim Phan, Yessica Haydee Gomez, Jessica Gorgui, Amira El-Messidi, Robert Gagnon, Stella Daskalopoulou |
| المصدر: | Artery Research, Vol 16 (2016) |
| بيانات النشر: | BMC, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Specialties of internal medicine LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Specialties of internal medicine, RC581-951, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Objective: To develop a model for the 1st trimester prediction of pre-eclampsia. Methods: In this prospective longitudinal study, women with high-risk singleton pregnancies were recruited and arterial stiffness was measured using applanation tonometry (SphygmoCor, AtCor) and compared between women who developed PE and those who had a normotensive pregnancy. Arterial stiffness and hemodynamics were assessed, in the 1st trimester, every 4 weeks thereafter, and at 6 weeks postpartum. Angiogenic biomarker concentrations (Quantikine, R&D Systems) were measured at each trimester and at 6 weeks postpartum, and a bilateral uterine artery Doppler (UAD) was performed in the 2nd trimester. Results: Of the 155 women recruited, 13 developed pre-eclampsia. Analyses adjusted for both maternal age and body mass index showed women who developed pre-eclampsia had significantly increased wave reflection and carotid-femoral pulse wave velocity (cfPWV) from the 1st trimester, throughout pregnancy, and at 6 weeks post-partum with a cfPWV:carotid-radial PWV mistmatch seen in the 1st and 3rd trimester (all p-values |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1876-4401 |
| Relation: | https://www.atlantis-press.com/article/125930400/view; https://doaj.org/toc/1876-4401 |
| DOI: | 10.1016/j.artres.2016.10.017 |
| URL الوصول: | https://doaj.org/article/40602d1f23f8450fbef8f4214d85e5be |
| رقم الأكسشن: | edsdoj.40602d1f23f8450fbef8f4214d85e5be |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 18764401 |
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| DOI: | 10.1016/j.artres.2016.10.017 |