دورية أكاديمية
BISOPROLOL AND METFORMIN IN PATIENTS WITH ARTERIAL HYPERTENSION AND METABOLIC SYNDROME
| العنوان: | BISOPROLOL AND METFORMIN IN PATIENTS WITH ARTERIAL HYPERTENSION AND METABOLIC SYNDROME |
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| المؤلفون: | V. A. Nevzorova, N. V. Zakcharchuk, O. V. Nastradin, O. G. Pomogalova |
| المصدر: | Рациональная фармакотерапия в кардиологии, Vol 3, Iss 5, Pp 54-57 (2015) |
| بيانات النشر: | Столичная издательская компания, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Therapeutics. Pharmacology LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | бисопролол, метформин, артериальная гипертония, метаболический синдром, Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Aim. To compare efficacy of bisoprolol and bisoprolol+metformin combination in patients with arterial hypertension (AH) and metabolic syndrome (MS).Material and methods. 20 patients with AH and MS were involved in the study. They were randomized in 2 groups, 10 patients in each group. Patients of the 1st group received bisoprolol. Patients of the 2nd group received combination of bisoprolol and metformin. Blood pressure (BP), body mass index (BMI), carbohydrate metabolism, lipid profile, microalbuminuria (МАU) level was determined before, within and at the end of 24-week treatment.Results. Both treatments resulted in similar reduction in BP. Reduction of BMI and insulin plasma concentration was more significant in patients received combined therapy. Both treatments improved lipid profile and reduced MAU.Conclusion. Bisoprolol has positive effect on pathogenic mechanisms of AH and MS. Metformin additionally improves carbohydrate and lipid metabolism. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Russian |
| تدمد: | 1819-6446 2225-3653 |
| Relation: | http://www.rpcardio.ru/jour/article/view/546; https://doaj.org/toc/1819-6446; https://doaj.org/toc/2225-3653 |
| DOI: | 10.1234/1819-6446-2007-5-54-57 |
| URL الوصول: | https://doaj.org/article/40d0cc76a1ba480eb415bfb6d39a1dbb |
| رقم الأكسشن: | edsdoj.40d0cc76a1ba480eb415bfb6d39a1dbb |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18196446 22253653 |
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| DOI: | 10.1234/1819-6446-2007-5-54-57 |