دورية أكاديمية
Serum cholinesterase is associated with incident diabetic retinopathy: the Shanghai Nicheng cohort study
| العنوان: | Serum cholinesterase is associated with incident diabetic retinopathy: the Shanghai Nicheng cohort study |
|---|---|
| المؤلفون: | Rong Yu, Xiaoqi Ye, Xiangning Wang, Qiang Wu, Lili Jia, Keqing Dong, Zhijun Zhu, Yuqian Bao, Xuhong Hou, Weiping Jia |
| المصدر: | Nutrition & Metabolism, Vol 20, Iss 1, Pp 1-9 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Nutritional diseases. Deficiency diseases |
| مصطلحات موضوعية: | Diabetic retinopathy, Serum cholinesterase, Metabolism, Observational study, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627 |
| الوصف: | Abstract Background Serum cholinesterase (ChE) is positively associated with incident diabetes and dyslipidemia. We aimed to investigate the relationship between ChE and the incidence of diabetic retinopathy (DR). Methods Based on a community-based cohort study followed for 4.6 years, 1133 participants aged 55–70 years with diabetes were analyzed. Fundus photographs were taken for each eye at both baseline and follow-up investigations. The presence and severity of DR were categorized into no DR, mild non-proliferative DR (NPDR), and referable DR (moderate NPDR or worse). Binary and multinomial logistic regression models were used to estimate the risk ratio (RR) and 95% confidence interval (CI) between ChE and DR. Results Among the 1133 participants, 72 (6.4%) cases of DR occurred. The multivariable binary logistic regression showed that the highest tertile of ChE (≥ 422 U/L) was associated with a 2.01-fold higher risk of incident DR (RR 2.01, 95%CI 1.01-4.00; P for trend |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1743-7075 |
| Relation: | https://doaj.org/toc/1743-7075 |
| DOI: | 10.1186/s12986-023-00743-2 |
| URL الوصول: | https://doaj.org/article/aedc40ec62e54a2aae296fe34878ce2b |
| رقم الأكسشن: | edsdoj.40ec62e54a2aae296fe34878ce2b |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 17437075 |
|---|---|
| DOI: | 10.1186/s12986-023-00743-2 |