دورية أكاديمية
Noncontact Conjunctiva: A Better Mitomycin C Application Site for Trabeculectomy
| العنوان: | Noncontact Conjunctiva: A Better Mitomycin C Application Site for Trabeculectomy |
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| المؤلفون: | Yunru Liao, Yafen Liu, Xinbo Gao, Jiawei Ren, Huishan Lin, Yao Liu, Wei Huang, Chengguo Zuo, Mingkai Lin |
| المصدر: | Ophthalmology and Therapy, Vol 12, Iss 3, Pp 1723-1735 (2023) |
| بيانات النشر: | Adis, Springer Healthcare, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Ophthalmology |
| مصطلحات موضوعية: | Trabeculectomy, Mitomycin C, Application position, Ophthalmology, RE1-994 |
| الوصف: | Abstract Introduction Bleb scarring is the most important complication of trabeculectomy. Changing the application position of mitomycin C (MMC) during trabeculectomy might affect the surgery outcome. Our aim is to compare the effectiveness and safety of intraocular pressure (IOP) lowering in two different application sites of mitomycin in trabeculectomy. Methods This retrospective trial compared the surgical outcomes of 177 eyes that underwent trabeculectomy with adjunctive mitomycin C. In 70 eyes, an MMC-soaked sponge was applied under the scleral flap without touching Tenon’s capsule. In 107 eyes, an MMC-soaked sponge was applied under the scleral flap covered by Tenon’s capsule. Outcome measures were the IOP, best-corrected visual acuity (BCVA), success rates, and incidence of complications. Results Within both groups, a highly significant IOP reduction was seen during follow-up. The effectiveness in reducing IOP and the change in best-corrected visual acuity (BCVA) were similar between the two groups. Thin-walled blebs and postoperative hypotony were seen more often when MMC-soaked sponges were applied under the scleral flap covered by Tenon’s capsule (P = 0.008 and P = 0.012, respectively). There was no significant difference in BCVA or other complications in either group. Conclusion Since the effectiveness of IOP reduction was similar between both groups and with a low incidence of thin-walled blebs and hypotony, the subscleral application without touching Tenon’s capsule seems to be the safer application site of MMC during trabeculectomy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2193-8245 2193-6528 |
| Relation: | https://doaj.org/toc/2193-8245; https://doaj.org/toc/2193-6528 |
| DOI: | 10.1007/s40123-023-00706-z |
| URL الوصول: | https://doaj.org/article/4165448b200b4a569867aa7e8c336dc3 |
| رقم الأكسشن: | edsdoj.4165448b200b4a569867aa7e8c336dc3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 21938245 21936528 |
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| DOI: | 10.1007/s40123-023-00706-z |