دورية أكاديمية
Evaluation of Prognostic Factors for the Parotid Cancer Treated With Surgery and Postoperative Radiotherapy
| العنوان: | Evaluation of Prognostic Factors for the Parotid Cancer Treated With Surgery and Postoperative Radiotherapy |
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| المؤلفون: | Yong-Hyub Kim, Woong-Ki Chung, Jae-Uk Jeong, Ick Joon Cho, Mee Sun Yoon, Ju-Young Song, Taek-Keun Nam, Sung-Ja Ahn, Dong Hoon Lee, Tae Mi Yoon, Joon Kyoo Lee, Sang Chul Lim |
| المصدر: | Clinical and Experimental Otorhinolaryngology, Vol 13, Iss 1, Pp 69-76 (2020) |
| بيانات النشر: | Korean Society of Otorhinolaryngology-Head and Neck Surgery, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medicine LCC:Otorhinolaryngology |
| مصطلحات موضوعية: | parotid neoplasms, adjuvant radiotherapy, prognosis, metastases, Medicine, Otorhinolaryngology, RF1-547 |
| الوصف: | Objectives To investigate the prognostic factors and treatment outcomes of primary parotid carcinoma treated with surgery and postoperative radiotherapy (PORT). Methods We reviewed retrospectively 57 patients with primary parotid carcinoma who were treated with surgery and PORT between 2005 and 2014. Superficial parotidectomy was performed in 19 patients, total parotidectomy in 10 patients, and total parotidectomy with lymph node dissection in 28 patients PORT on the tumor bed was performed in 41 patients, while PORT on tumor bed and ipsilateral cervical lymph nodes was performed in 16 patients. Results With a median follow-up of 66 months, the 5-year overall survival, disease-free survival, locoregional control, and distant control rates were 77.0%, 60.2%, 77.6%, and 72.8%, respectively. The 5-year overall survival by stage was 100%, 100%, 80.0%, and 46.4% in stage I, II, III, and IV, respectively. Recurrences at primary lesions were found in seven patients, while at cervical nodes in six patients. Distant recurrences were developed in 12 patients. No patient with the low and intermediate histologic grade developed distant failure. As prognostic factors, the histologic grade for overall survival (P=0.005), pathological T-stage (P=0.009) and differentiation grade (P=0.009) for disease-free survival, pathological T-stage for locoregional control (P=0.007), and lympho-vascular invasion (P=0.023) for distant recurrence were significant on multivariate analysis. Conclusion This study revealed that differentiation grade, histologic grade, pathological T-stage, and lympho-vascular invasion were significant independent prognostic factors on clinical outcomes. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1976-8710 2005-0720 |
| Relation: | http://www.e-ceo.org/upload/pdf/ceo-2019-00388.pdf; https://doaj.org/toc/1976-8710; https://doaj.org/toc/2005-0720 |
| DOI: | 10.21053/ceo.2019.00388 |
| URL الوصول: | https://doaj.org/article/4222c64386a14d059e5d49c342205bea |
| رقم الأكسشن: | edsdoj.4222c64386a14d059e5d49c342205bea |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19768710 20050720 |
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| DOI: | 10.21053/ceo.2019.00388 |