دورية أكاديمية
SPASMOLYTIC EFFECT OF ANETHUM GRAVEOLENS L. METHANOL EXTRACT ON ISOLATED RAT ILEUM
العنوان: | SPASMOLYTIC EFFECT OF ANETHUM GRAVEOLENS L. METHANOL EXTRACT ON ISOLATED RAT ILEUM |
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المؤلفون: | Marija Gočmanac Ignjatović, Dušanka Kitić, Milica Kostić, Bojana Miladinović, Milica Milutinović, Milica Veljković, Suzana Branković |
المصدر: | Acta Medica Medianae, Vol 54, Iss 2, Pp 5-10 (2015) |
بيانات النشر: | University in Nis, Faculty of Medicine, 2015. |
سنة النشر: | 2015 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | dill, Anethum graveolens L., methanol extract, acetylcholine, rat, ileum, Medicine |
الوصف: | Anethum graveolens L. is a member of the Apiaceae family and more commonly known as dill. Dill has been used for gastrointestinal ailments such as flatulence, indigestion, stomach ache and colic. It has therapeutic effects such as mucosal protective, antisecretory, antimicrobial, antispasmodic, antihypercholesterolaemic and antihyperlipidaemic. The aim of our study was to examine the effects of the dill methanol extract on spontaneous and acetylcholine-induced contractions on isolated rat ileum. Segments of the rat ileum were suspended in an organ bath. The isolated ileum had been treated with the methanol extract of dill in cumulative concentrations (0.003- 1mg/mL). In the second series of experiments, acetylcholine (5-1500nM) was cumulatively added to the bath in the absence and presence of methanol extract of dill (0.3-1mg/mL). Cumulative concentrations of methanol extract of dill significantly reduced the spontaneous rat ileum contractions (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0365-4478 1821-2794 |
Relation: | http://publisher.medfak.ni.ac.rs/2015-html/2015%202-broj/Celi%20radovi%20pdf%202015-2/Marija%20Gocmanac.pdf; https://doaj.org/toc/0365-4478; https://doaj.org/toc/1821-2794 |
DOI: | 10.5633/amm.2015.0201 |
URL الوصول: | https://doaj.org/article/424998b5fab347a983a753e4e98a9d2b |
رقم الأكسشن: | edsdoj.424998b5fab347a983a753e4e98a9d2b |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 03654478 18212794 |
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DOI: | 10.5633/amm.2015.0201 |