دورية أكاديمية
Ocular squamous cell carcinoma in Holstein cows from the South of Brazil
| العنوان: | Ocular squamous cell carcinoma in Holstein cows from the South of Brazil |
|---|---|
| المؤلفون: | Gabrielle A. Fornazari, Juliana Kravetz, Matti Kiupel, Dodd Sledge, Ivan Roque De Barros Filho, Fabiano Montiani-Ferreira |
| المصدر: | Veterinary World, Vol 10, Iss 12, Pp 1413-1420 (2017) |
| بيانات النشر: | Veterinary World, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Animal culture LCC:Veterinary medicine |
| مصطلحات موضوعية: | bovine, histologic classification, ophthalmology, p16, p53, tumor behavior, Animal culture, SF1-1100, Veterinary medicine, SF600-1100 |
| الوصف: | Aim: The aim of this study was to investigate 10 cases of bovine ocular squamous cell carcinoma (OSCC) diagnosed in Holstein or Holstein-crosses cows. Materials and Methods: The investigation was performed exclusively in OSCC cases diagnosed in the State of Parana and Santa Catarina. A combination of two previously existing histopathological classifications systems was used. The tissue samples were tested for immunoexpression of p53 and p16 and polymerase chain reaction (PCR) for bovine herpesvirus and papillomavirus. Results: A positive correlation between number of mitotic figures and tissue invasion was found. Anaplasia parameters did not correlate well with tumor invasion of deeper tissues and mitotic counts. Six of 10 OSCC cases were in animals with heavily pigmented eyes. Immunoexpression of p53 and p16 was observed in 3 cases each. Bovine herpesvirus and papillomavirus were not detected by PCR. Conclusion: Our results indicate that OSCC occurrence is most likely multifactorial with genetic, phenotypic, and environmental influences contributing to the pathogenesis of the disease. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1413-1420 0972-8988 2231-0916 |
| Relation: | http://www.veterinaryworld.org/Vol.10/December-2017/2.pdf; https://doaj.org/toc/0972-8988; https://doaj.org/toc/2231-0916 |
| DOI: | 10.14202/vetworld.2017.1413-1420 |
| URL الوصول: | https://doaj.org/article/44236788a38a4eb2a769dd5e07e8d29d |
| رقم الأكسشن: | edsdoj.44236788a38a4eb2a769dd5e07e8d29d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14131420 09728988 22310916 |
|---|---|
| DOI: | 10.14202/vetworld.2017.1413-1420 |